RSS 1.0William Harvey Research Institute
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Recent Submissions
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Investigation for Paediatric Cushing's Syndrome Using Twenty-Four-Hour Urinary Free Cortisol Determination.
(Karger Publishers, 2016-05-10)OBJECTIVE: Paediatric Cushing's syndrome (CS) remains a challenge to diagnose and exclude. We assessed the accuracy of 24-hour urinary free cortisol (UFC) determination in children referred for suspected CS. DESIGN: We ... -
Vagal determinants of exercise capacity.
(2017-05-18)Indirect measures of cardiac vagal activity are strongly associated with exercise capacity, yet a causal relationship has not been established. Here we show that in rats, genetic silencing of the largest population of ... -
A unique haplotype of RCCX copy number variation: from the clinics of congenital adrenal hyperplasia to evolutionary genetics
(2017-04-12)© 2017 Macmillan Publishers Limited, part of Springer Nature.There is a difficulty in the molecular diagnosis of congenital adrenal hyperplasia (CAH) due to the c.955C>T (p.(Q319*), formerly Q318X, rs7755898) variant of ... -
The Novel Lipid Mediator PD1n-3DPA: An Overview of the Structural Elucidation, Synthesis, Biosynthesis and Bioactions.
(2017-06-07)Resolvins, protectins and maresins are individual families of specialized pro-resolving mediators biosynthesized from the dietary n-3 polyunsaturated fatty acids eicosapentaenoic acid and docosahexaenoic acid. These ...
