• Baricitinib counteracts metaflammation thus protecting against diet-induced metabolic abnormalities in mice. 

  Collotta, D; Hull, W; Mastrocola, R; Chiazza, F; Cento, AS; Murphy, C; Verta, R; Alves, GF; Gaudioso, G; Fava, F (2020-05-12)

  OBJECTIVE: Recent evidence suggests a substantial pathogenic role for the Janus kinase (Jak)/signal transducer and activator of transcription (Stat) pathway in the development of the low grade chronic inflammatory response, ...

• APPROPRIATENESS OF PRESCRIBING OF DIRECT ORAL ANTICOAGULANTS IN A UNIVERSITY TEACHING HOSPITAL NETWORK 

  Elechi, F; Antoniou, S; Kapil, V (2019-05)

• Effects of Rehabilitation Interventions on Clinical Outcomes in Critically Ill Patients: Systematic Review and Meta-Analysis of Randomized Controlled Trials. 

  Waldauf, P; Jiroutková, K; Krajčová, A; Puthucheary, Z; Duška, F (Lippincott, Williams & Wilkins, 2020-04-28)

  OBJECTIVES: To assess the impact of rehabilitation in ICU on clinical outcomes. DATA SOURCES: Secondary data analysis of randomized controlled trials published between 1998 and October 2019 was performed in accordance with ...

• TRANSDERMAL CLONIDINE IN DIFFICULT-TO-TREAT HYPERTENSION PATIENTS ATTENDING A SPECIALIST BP CLINIC IN THE UNITED KINGDOM 

  Kapil, V; Louthan, J; Hamedi, N; Antoniou, S; Lobo, M (Lippincott, Williams & Wilkins, 2017-09)

  Objective: Poor adherence to anti-hypertensive therapy contributes to sub-optimal hypertension control rates and may relate to medication posology and adverse drug reactions. Transdermal clonidine applied once-weekly may ...

• Antibody-mediated inhibition of syndecan-4 dimerisation reduces interleukin (IL)-1 receptor trafficking and signalling. 

  Godmann, L; Bollmann, M; Korb-Pap, A; König, U; Sherwood, J; Beckmann, D; Mühlenberg, K; Echtermeyer, F; Whiteford, J; De Rossi, G (BMJ Publishing Group, 2020-04)

  OBJECTIVE: Syndecan-4 (sdc4) is a cell-anchored proteoglycan that consists of a transmembrane core protein and glucosaminoglycan (GAG) side chains. Binding of soluble factors to the GAG chains of sdc4 may result in the ...

• Antithrombotic therapy in patients with recent stroke and atrial fibrillation. 

  Saberwal, B; Ioannou, A; Lim, WY; Beirne, A-M; Chow, AW; Tousoulis, D; Ahsan, S; Papageorgiou, N (2020-04-07)

  Atrial fibrillation (AF) is a common arrhythmia which carries a significant risk of stroke. Secondary prevention, in particular in the acute phase of stroke with anti-thrombotic therapy has not been validated. The aim of ...

• A combination of LCPUFA ameliorates airway inflammation in asthmatic mice by promoting pro-resolving effects and reducing adverse effects of EPA 

  Fussbroich, D; Colas, RA; Eickmeier, O; Trischler, J; Jerkic, SP; Zimmermann, K; Goepel, A; Schwenger, T; Schaible, A; Henrich, D (2020-05)

• Antithrombotic therapy in patients with acute coronary syndrome complicated by cardiogenic shock or out-of-hospital cardiac arrest: a Joint Position Paper from the European Society of Cardiology (ESC) Working Group on Thrombosis, in association with the Acute Cardiovascular Care Association (ACCA) and European Association of Percutaneous Cardiovascular Interventions (EAPCI). 

  Gorog, DA; Price, S; Sibbing, D; Baumbach, A; Capodanno, D; Gigante, B; Halvorsen, S; Huber, K; Lettino, M; Leonardi, S (2020-02-12)

  Timely and effective antithrombotic therapy is critical to improving outcome, including survival, in patients with acute coronary syndrome (ACS). Achieving effective platelet inhibition and anticoagulation, with minimal ...

• Evaluation of the Efficacy of Computed Tomographic Coronary Angiography in Assessing Coronary Artery Morphology and Physiology: Rationale and Study Design. 

  Ramasamy, A; Safi, H; Moon, JC; Andiapen, M; Rathod, KS; Maurovich-Horvat, P; Bajaj, R; Serruys, PW; Mathur, A; Baumbach, A (2020)

  Computed tomographic coronary angiography (CTCA) is a non-invasive imaging modality, which allows plaque burden and composition assessment and detection of plaque characteristics associated with increased vulnerability. ...

• A risk scoring system to predict coronary stent thrombosis 

  Malik, N; Banning, AS; Belger, M; Fakhouri, W; Graham-Clarke, PL; Banning, A; Baumbach, A; Blackman, DJ; de Belder, A; Lefevre, T (Taylor & Francis Online, 2017-05)

  Objective: Stent thrombosis (ST) is a potentially life-threatening complication of percutaneous coronary intervention (PCI). We aimed to develop a scoring system to predict the risk of ST following PCI. Research design ...

• Computerised Methodologies for Non-Invasive Angiography-Derived Fractional Flow Reserve Assessment: A Critical Review 

  Ramasamy, A; Jin, C; Tufaro, V; Bajaj, R; Kilic, Y; Safi, H; Amersey, R; Jones, D; Torii, R; Lansky, A (2020-04-20)

• Predictive value of the QFR in detecting vulnerable plaques in non-flow limiting lesions: a combined analysis of the PROSPECT and IBIS-4 study. 

  Safi, H; Bourantas, CV; Ramasamy, A; Zanchin, T; Bär, S; Tufaro, V; Jin, C; Torii, R; Karagiannis, A; Reiber, JHC (2020-06)

  Studies have shown that the quantitative flow ratio (QFR), recently introduced to assess lesion severity from coronary angiography, provides useful prognostic information; however the additive value of this technique over ...

• Transcatheter aortic valve implantation via surgical subclavian versus direct aortic access: A United Kingdom analysis 

  Myat, A; Papachristofi, O; Trivedi, U; Bapat, V; Young, C; de Belder, A; Cockburn, J; Baumbach, A; Banning, AP; Blackman, DJ (2020-06-01)

• EAPCI Position Statement on Invasive Management of Acute Coronary Syndromes during the COVID-19 pandemic. 

  Chieffo, A; Stefanini, GG; Price, S; Barbato, E; Tarantini, G; Karam, N; Moreno, R; Buchanan, GL; Gilard, M; Halvorsen, S (2020-05-14)

  The coronavirus disease 2019 (COVID-19) pandemic poses an unprecedented challenge to healthcare worldwide. The infection can be life threatening and require intensive care treatment. The transmission of the disease poses ...

• 2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS). 

  Konstantinides, SV; Meyer, G; Becattini, C; Bueno, H; Geersing, G-J; Harjola, V-P; Huisman, MV; Humbert, M; Jennings, CS; Jiménez, D (2020-01-21)

• 2018 ESC/EACTS Guidelines on myocardial revascularization. 

  Neumann, F-J; Sousa-Uva, M; Ahlsson, A; Alfonso, F; Banning, AP; Benedetto, U; Byrne, RA; Collet, J-P; Falk, V; Head, SJ (2019-01-07)

• 2018 ESC/EACTS Guidelines on myocardial revascularization. 

  Sousa-Uva, M; Neumann, F-J; Ahlsson, A; Alfonso, F; Banning, AP; Benedetto, U; Byrne, RA; Collet, J-P; Falk, V; Head, SJ (2019-01-01)

• 2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: The Task Force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). 

  Ibanez, B; James, S; Agewall, S; Antunes, MJ; Bucciarelli-Ducci, C; Bueno, H; Caforio, ALP; Crea, F; Goudevenos, JA; Halvorsen, S (2018-01-07)

• The Big Data Sjögren Consortium: a project for a new data science era. 

  Acar-Denizli, N; Kostov, B; Ramos-Casals, M; Sjögren Big Data Consortium (2019-05)

• The British Society for Rheumatology guideline for the management of adults with primary Sjogren's Syndrome 

  Price, EJ; Rauz, S; Tappuni, AR; Sutcliffe, N; Hackett, KL; Barone, F; Granata, G; Ng, W-F; Fisher, BA; Bombardieri, M (Oxford University Press (OUP), 2017-06-28)

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