• THU-236-YI Oxysterol treatment causes indirect stellate cell activation: a potential mechanism linking steroid metabolising enzyme dysregulation with fibrosis 

  Miller, H; Garrido, P; Li, W; Kumar, R; Gines, I; Nikolaou, N; Potter, T; Bailey, M; Karpe, F; Neville, M (Elsevier, 2024-06)

• Hemoadsorption: consensus report of the 30th Acute Disease Quality Initiative workgroup. 

  Bellomo, R; Ankawi, G; Bagshaw, SM; Baldwin, I; Basu, R; Bottari, G; Cantaluppi, V; Clark, W; De Rosa, S; Forni, LG (Oxford University Press, 2024-04-15)

  Adsorption-based extracorporeal therapies have been subject to technical developments and clinical application for close to five decades. More recently, new technological developments in membrane and sorbent manipulation ...

• The effect of high protein dosing in critically ill patients: an exploratory, secondary Bayesian analyses of the EFFORT Protein trial. 

  Haines, RW; Granholm, A; Puthucheary, Z; Day, AG; Bear, DE; Prowle, JR; Heyland, DK (Elsevier, 2024-10-24)

  BACKGROUND: The EFFORT Protein trial assessed the effect of high vs usual dosing of protein in adult ICU patients with organ failure. This study provides a probabilistic interpretation and evaluates heterogeneity in treatment ...

• Protocolized fluid balance neutralization during continuous renal replacement therapy. 

  Murugan, R; Prowle, J; Beaubien-Souligny, W (Springer Nature, 2024-10-31)

• Routine measurement of cardiometabolic disease risk factors in primary care in England before, during, and after the COVID-19 pandemic: A population-based cohort study. 

  Ho, FK; Dale, C; Mizani, MA; Bolton, T; Pearson, ER; Valabhji, J; Delles, C; Welsh, P; Nakada, S; Mackay, D (Public Library of Science, 2024-11-26)

  BACKGROUND: This study estimated to what extent the number of measurements of cardiometabolic risk factors (e.g., blood pressure, cholesterol, glycated haemoglobin) were impacted by the COVID-19 pandemic and whether these ...

• Left ventricular apical aneurysms and outcomes in hypertrophic cardiomyopathy 

  Malcolmson, J; Amarin, M; Davies, W; Husselbury, T; Mezzanotte, G; Learoyd, A; Petersen, SE; O'mahony, C; Mohiddin, SA (Oxford University Press (OUP), 2024-10-28)

• Routine measurement of cardiometabolic disease risk factors in primary care in England before, during, and after the COVID-19 pandemic: a population-based cohort study 

  Petersen, S (Public Library of Science, 2024-11-26)

  Background This study estimated to what extent the number of measurements of cardiometabolic risk factors (e.g., blood pressure, cholesterol, glycated haemoglobin) were impacted by the COVID-19 pandemic and whether these ...

• Leukocyte telomere length and conduction system ageing 

  Petersen, S; Aung, N

  Objective: Deterioration of the cardiac conduction system is an important manifestation of cardiac ageing. Cellular ageing is accompanied by telomere shortening and telomere length is often regarded as a marker of biological ...

• Opportunities and Challenges for the Use of Human Samples in Translational Cardiovascular Research. A Scientific Statement of the ESC Working Group on Cellular Biology of the Heart, the ESC Working Group on Cardiovascular Surgery, the ESC Council on Basic Cardiovascular Science, the ESC Scientists of Tomorrow, the European Association of Percutaneous Cardiovascular Interventions of the ESC and the Heart Failure Association of the ESC 

  Petersen, S

• Cost-effectiveness of a novel AI technology to quantify coronary inflammation and cardiovascular risk in patients undergoing routine Coronary Computed Tomography Angiography. 

  Tsiachristas, A; Chan, K; Wahome, E; Kearns, B; Patel, P; Lyasheva, M; Syed, N; Fry, S; Halborg, T; West, H (Oxford University Press, 2024-09-28)

  AIMS: Coronary Computed Tomography Angiography (CCTA) is a first line investigation for chest pain in patients with suspected obstructive coronary artery disease (CAD). However, many acute cardiac events occur in the absence ...

• Blood biomarkers to detect functional impairment in adult patients with repaired Tetralogy of Fallot 

  Alborikan, S; Badian, S; Althunyyan, AT; Pandya, B; Bhan, A; Cullen, S; Monteiro, RP; Bingcang, R; Encarnacion, D; Bhattacharyya, S (Oxford University Press (OUP), 2024-10-28)

• Contemporary epidemiology of hospitalised heart failure with reduced versus preserved ejection fraction in England: a retrospective, cohort study of whole-population electronic health records. 

  Fletcher, RA; Rockenschaub, P; Neuen, BL; Walter, IJ; Conrad, N; Mizani, MA; Bolton, T; Lawson, CA; Tomlinson, C; Logothetis, SB (Elsevier, 2024-11)

  BACKGROUND: Heart failure is common, complex, and often associated with coexisting chronic medical conditions and a high mortality. We aimed to assess the epidemiology of people admitted to hospital with heart failure with ...

• A Comprehensive Review of Clinical Studies Applying Flow-Mediated Dilation 

  Ahn, Y; Aung, N; Ahn, H-S (MDPI, 2024-11-08)

  Flow-mediated dilation (FMD) is a noninvasive method to evaluate vascular endothelial function, which manifests the vascular inflammatory response, cell proliferation, and autoregulation. Since FMD is noninvasive and ...

• Abstract 4139238: A Multi-Population-First Approach Leveraging UK Biobank (UKBB) and All of Us (AoU) Datasets Reveals Higher Cardiomyopathy Variant Burden in Individuals with Myocarditis 

  Gurumoorthi, M; Hesse, K; Asatryan, B; Shah, R; Sharaf Dabbagh, G; Wolfe, R; Shyam Sundar, V; Mohiddin, S; Aung, N; Khanji, M (Wolters Kluwer, 2024-11-12)

• Cardiovascular magnetic resonance versus echocardiography derived left ventricular ejection fraction for decision-making. 

  Dhall, E; Mahmood, A; Aung, N; Khanji, MY (Taylor & Francis, 2024-11-14)

• Genetic basis of right and left ventricular heart shape. 

  Burns, R; Young, WJ; Aung, N; Lopes, LR; Elliott, PM; Syrris, P; Barriales-Villa, R; Sohrabi, C; Petersen, SE; Ramírez, J (2024-11-14)

  Heart shape captures variation in cardiac structure beyond traditional phenotypes of mass and volume. Although observational studies have demonstrated associations with cardiometabolic risk factors and diseases, its genetic ...

• Pro-resolving lipid mediators and therapeutic innovations in resolution of inflammation. 

  Peh, HY; Chen, J (2024-11-18)

  This review summarizes findings presented at the 19th World Congress of Basic & Clinical Pharmacology 2023 (Glasgow, Scotland, July 3rd to 7th, 2023) from 8 speakers in the field of resolution of inflammation, resolution ...

• Cross-Sectional Survey to Assess Hospital System Readiness for Hemorrhage During and After Cesarean Delivery in Africa. 

  Crowther, M; Dyer, RA; Bishop, DG; Bulamba, F; Maswime, S; Pearse, RM; Biccard, BM; African Partnership for Perioperative and Critical Care Research (APPRISE) Investigators (Lippincott Wolters Kluwer, 2024-11-06)

  BACKGROUND: Mothers in Africa are 50 times more likely to die after cesarean delivery (CD) than in high-income countries, largely due to hemorrhage. It is unclear whether countries across Africa are adequately equipped to ...

• Abstract 4145199: Prevalence and Prognostic Implications of Sleep Disordered Breathing in Hypertrophic Cardiomyopathy 

  Karim, S; Chahal, A; Venkataraman, S; Deshmukh, A; Siontis, K; mansukhani, M; Konecny, T; Khanji, M; Petersen, S; Geske, J (Wolters Kluwer, 2024-11-12)

• The effects of preoperative moderate to severe anaemia on length of hospital stay A propensity score-matched analysis in non-cardiac surgery patients 

  Bulte, CSE; Boer, C; Hemmes, SNT; Neto, AS; Binnekade, JM; Hedenstierna, G; Jaber, S; Hiesmayr, M; Hollmann, MW; Mills, GH (European Society of Anaesthesiology and Intensive Care, 2021-01-04)

  BACKGROUND Anaemia is frequently recorded during preoperative screening and has been suggested to affect outcomes after surgery negatively. OBJECTIVES The objectives were to assess the frequency of moderate to severe ...

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