• Efficient generation of a stable CHO-K1 cell line overexpressing the human water channel Aquaporin-5 as tool to generate therapeutic antibodies. 

  Corsiero, E; Jagemann, L; Bombardieri, M; Nia, S

• One year in review 2020: pathogenesis of primary Sjogren's syndrome 

  Bombardieri, M; Argyropoulou, OD; Ferro, F; Coleby, R; Pontarini, E; Governato, G; Lucchesi, D; Fulvio, G; Tzioufas, AG; Baldini, C (2020)

• Blocking T cell co-stimulation in primary Sjögren's syndrome: rationale, clinical efficacy and modulation of peripheral and salivary gland biomarkers. 

  Pontarini, E; Verstappen, GM; Grigoriadou, S; Kroese, FGM; Bootsma, H; Bombardieri, M (2020)

  There is accumulating evidence that patients with primary Sjögren's syndrome (pSS) display aberrant CD4+ T cell responses, both in the peripheral compartment and in the inflamed salivary glands. CD4+ T cell abnormalities ...

• One year in review 2020: pathogenesis of primary Sjögren's syndrome. 

  Bombardieri, M; Argyropoulou, OD; Ferro, F; Coleby, R; Pontarini, E; Governato, G; Lucchesi, D; Fulvio, G; Tzioufas, AG; Baldini, C (2020)

  The pathogenesis of primary Sjögren's syndrome (pSS) remains poorly understood. However, important efforts have been made during the last few months. In this review, following the others of this series we will summarise ...

• CD8+ tissue-resident memory T cells are expanded in primary Sjögren's disease and can be therapeutically targeted by CD103 blockade. 

  Mauro, D; Lin, X; Pontarini, E; Wehr, P; Guggino, G; Tang, Y; Deng, C; Gandolfo, S; Xiao, F; Rui, K (2024-05-22)

  OBJECTIVE: Tissue-resident memory cells (Trm) are a subset of T cells residing persistently and long-term within specific tissues that contribute to persistent inflammation and tissue damage. We characterised the phenotype ...

• Derived myeloid lineage induced pluripotent stem as a platform to study human C-C chemokine receptor type 5Δ32 homozygotes. 

  Chen, G; Calcaterra, F; Ma, Y; Ping, X; Pontarini, E; Yang, D; Oriolo, F; Yu, Z; Cancellara, A; Mikulak, J (Elsevier, 2023-10-26)

  The C-C chemokine receptor type 5 (CCR5) expressed on immune cells supports inflammatory responses by directing cells to the inflammation site. CCR5 is also a major coreceptor for macrophage tropic human immunodeficiency ...

• A redox-based characterization of human immune cell subsets by polychromatic flow cytometry. 

  Pitsillidou, C; Muradore, I; Pontarini, E; Bertolotti, M; Roberto, A (2023-12-15)

  Cellular redox state determinants are traditionally studied using fluorescent microscopy and immunoblot analysis; however, no procedure has been developed for simultaneous measurement in various immune cell subsets. Here, ...

• Molecular portrait of chronic joint diseases: Defining endotypes toward personalized medicine. 

  Ghirardi, GM; Delrosso, CA; Nerviani, A; Boutet, M-A (2024-01-19)

  Joint diseases affect hundreds of millions of people worldwide, and their prevalence is constantly increasing. To date, despite recent advances in the development of therapeutic options for most rheumatic conditions, a ...

• Axl and MerTK regulate synovial inflammation and are modulated by IL-6 inhibition in rheumatoid arthritis. 

  Nerviani, A; Boutet, M-A; Ghirardi, GM; Goldmann, K; Sciacca, E; Rivellese, F; Pontarini, E; Prediletto, E; Abatecola, F; Caliste, M (2024-03-16)

  The TAM tyrosine kinases, Axl and MerTK, play an important role in rheumatoid arthritis (RA). Here, using a unique synovial tissue bioresource of patients with RA matched for disease stage and treatment exposure, we assessed ...

• Exercise therapy for tendinopathy: a mixed-methods evidence synthesis exploring feasibility, acceptability and effectiveness. 

  Cooper, K; Alexander, L; Brandie, D; Brown, VT; Greig, L; Harrison, I; MacLean, C; Mitchell, L; Morrissey, D; Moss, RA (2023-10)

  BACKGROUND: Tendinopathy is a common, painful and functionally limiting condition, primarily managed conservatively using exercise therapy. REVIEW QUESTIONS: (i) What exercise interventions have been reported in the ...

• There is no bilateral deficit of torque and rate of torque development of knee extensors during isometric exertion when measured by two independent isokinetic machines 

  Bulzing, RAV; Miller, SC; Oliveira, CG (2023)

• Predicting the outcome of plantar heel pain in adults: a systematic review of prognostic factors 

  Gulle, H; Morrissey, D; Tan, XL; Cotchett, M; Miller, SC; Jeffrey, AB; Prior, T (2023)

• 193 Can we predict the outcome for recovery of plantar heel pain? An international prospective cohort study 

  Gulle, H; Prior, T; Miller, S; Birn-Jeffery, A; Morrissey, D; Abstracts (BMJ, 2022-02)

• Running-Related Injury Incidence: Does It Correlate with Kinematic Sub-groups of Runners? A Scoping Review. 

  Adamson, L; Vandamme, L; Prior, T; Miller, SC (2024-01-27)

  BACKGROUND: Historically, kinematic measures have been compared across injured and non-injured groups of runners, failing to take into account variability in kinematic patterns that exist independent of injury, and resulting ...

• Biomechanical parameters of the golf swing associated with lower back pain: A systematic review. 

  Watson, M; Coughlan, D; Clement, ND; Murray, IR; Murray, AD; Miller, SC (2024-03-06)

  Low back pain (LBP) is the most common injury in golfers of all abilities. The primary aim of this review was to improve understanding of human golf swing biomechanics associated with LBP. A systematic review using the ...

• Screening siRNA efficacy using high throughput fluorescence system in vitro 

  Deniz, M; Thorup, AS; Dell'Accio, F (2022)

• SCREENING SIRNA EFFICACY USING HIGH THROUGHPUT FLUORESCENCE SYSTEM IN VITRO 

  Deniz, M; Thorup, A-S; Dell'Accio, F (2022)

• BLOCKING ROR2 IMPROVES CARTILAGE INTEGRITY AND PROVIDES PAIN RELIEF IN OSTEOARTHRITIS, IN PART BY MODULATING YAP SIGNALLING 

  Thorup, A-S; Wilson, J; Strachan, D; Caxaria, S; Poulet, B; Thomas, B; Eldridge, S; Nalesso, G; Whiteford, J; Pitzalis, C (2022)

• SCREENING SIRNA EFFICACY USING HIGH THROUGHPUT FLUORESCENCE SYSTEM IN VITRO. 

  Deniz, M; Thorup, A-S; Dell'Accio, F (Elsevier, 2022-04)

• Implementing treat-to-target urate-lowering therapy during hospitalisations for gout flares. 

  Russell, MD; Ameyaw-Kyeremeh, L; Dell'Accio, F; Lapham, H; Head, N; Stovin, C; Patel, V; Clarke, BD; Nagra, D; Alveyn, E (Oxford University Press, 2023-10-31)

  OBJECTIVES: To evaluate a strategy designed to optimise care and increase uptake of urate-lowering therapy (ULT) during hospitalisations for gout flares. METHODS: We conducted a prospective cohort study to evaluate a ...

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