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    AuthorBaumbach, A (12)Mathur, A (10)Petersen, SE (9)Wragg, A (8)Pearse, RM (6)Ackland, GL (5)Aung, N (5)Dalli, J (5)Jain, AK (5)Jones, DA (5)... View MoreSubjectHumans (91)
    Middle Aged (91)
    Female (83)Male (81)Aged (68)Adult (50)Prospective Studies (21)Risk Factors (21)Percutaneous Coronary Intervention (20)Treatment Outcome (20)... View MoreDate Issued2020 - 2022 (11)2010 - 2019 (79)2006 - 2009 (1)
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    Characterisation of myocardial structure and function in adult-onset growth hormone deficiency using cardiac magnetic resonance. 

    Thomas, JDJ; Dattani, A; Zemrak, F; Burchell, T; Akker, SA; Gurnell, M; Grossman, AB; Davies, LC; Korbonits, M (2016-12)
    Growth hormone (GH) can profoundly influence cardiac function. While GH excess causes well-defined cardiac pathology, fewer data are available regarding the more subtle cardiac changes seen in GH deficiency (GHD). This ...
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    Prospective association between handgrip strength and cardiac structure and function in UK adults. 

    Beyer, SE; Sanghvi, MM; Aung, N; Hosking, A; Cooper, JA; Paiva, JM; Lee, AM; Fung, K; Lukaschuk, E; Carapella, V;... (2018)
    BACKGROUND: Handgrip strength, a measure of muscular fitness, is associated with cardiovascular (CV) events and CV mortality but its association with cardiac structure and function is unknown. The goal of this study was ...
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    The impact of menopausal hormone therapy (MHT) on cardiac structure and function: Insights from the UK Biobank imaging enhancement study. 

    Sanghvi, MM; Aung, N; Cooper, JA; Paiva, JM; Lee, AM; Zemrak, F; Fung, K; Thomson, RJ; Lukaschuk, E; Carapella, V;... (2018)
    BACKGROUND: The effect of menopausal hormone therapy (MHT)-previously known as hormone replacement therapy-on cardiovascular health remains unclear and controversial. This cross-sectional study examined the impact of MHT ...
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    Cantú syndrome with coexisting familial pituitary adenoma. 

    Marques, P; Spencer, R; Morrison, PJ; Carr, IM; Dang, MN; Bonthron, DT; Hunter, S; Korbonits, M (2018-03)
    CONTEXT: Pseudoacromegaly describes conditions with an acromegaly related physical appearance without abnormalities in the growth hormone (GH) axis. Acromegaloid facies, together with hypertrichosis, are typical manifestations ...
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    Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study. 

    Wijeysundera, DN; Pearse, RM; Shulman, MA; Abbott, TEF; Torres, E; Ambosta, A; Croal, BL; Granton, JT; Thorpe, KE; Grocott, MPW;... (2018-06-30)
    BACKGROUND: Functional capacity is an important component of risk assessment for major surgery. Doctors' clinical subjective assessment of patients' functional capacity has uncertain accuracy. We did a study to compare ...
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    The Effects of Cinacalcet in Older and Younger Patients on Hemodialysis: The Evaluation of Cinacalcet HCl Therapy to Lower Cardiovascular Events (EVOLVE) Trial. 

    Parfrey, PS; Drüeke, TB; Block, GA; Correa-Rotter, R; Floege, J; Herzog, CA; London, GM; Mahaffey, KW; Moe, SM; Wheeler, DC;... (2015-05-07)
    BACKGROUND AND OBJECTIVES: The calcimimetic cinacalcet reduced the risk of death or cardiovascular (CV) events in older, but not younger, patients with moderate to severe secondary hyperparathyroidism (HPT) who were receiving ...
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    Epidemiology, practice of ventilation and outcome for patients at increased risk of postoperative pulmonary complications: LAS VEGAS - an observational study in 29 countries. 

    LAS VEGAS investigators (2017-08)
    BACKGROUND: Limited information exists about the epidemiology and outcome of surgical patients at increased risk of postoperative pulmonary complications (PPCs), and how intraoperative ventilation was managed in these ...
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    Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double-Blind Randomized Controlled Trial. 

    MacDonald, TM; Williams, B; Webb, DJ; Morant, S; Caulfield, M; Cruickshank, JK; Ford, I; Sever, P; Mackenzie, IS; Padmanabhan, S;... (2017-11-18)
    BACKGROUND: Guidelines for hypertension vary in their preference for initial combination therapy or initial monotherapy, stratified by patient profile; therefore, we compared the efficacy and tolerability of these approaches. ...
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    Atypical risk factor profile and excellent long-term outcomes of young patients treated with primary percutaneous coronary intervention for ST-elevation myocardial infarction. 

    Rathod, KS; Jones, DA; Gallagher, S; Rathod, VS; Weerackody, R; Jain, AK; Mathur, A; Mohiddin, SA; Archbold, RA; Wragg, A;... (2016-02)
    INTRODUCTION: Several studies have examined the relationship between age and clinical outcomes in patients with ST-elevation myocardial infarction (STEMI) treated by primary percutaneous coronary intervention (PPCI). The ...
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    Genetically Predicted Body Mass Index and Breast Cancer Risk: Mendelian Randomization Analyses of Data from 145,000 Women of European Descent. 

    Guo, Y; Warren Andersen, S; Shu, X-O; Michailidou, K; Bolla, MK; Wang, Q; Garcia-Closas, M; Milne, RL; Schmidt, MK; Chang-Claude, J;... (2016-08)
    BACKGROUND: Observational epidemiological studies have shown that high body mass index (BMI) is associated with a reduced risk of breast cancer in premenopausal women but an increased risk in postmenopausal women. It is ...
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