Quantifying stochasticity in the aging DNA methylome.
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Accepted version
Embargoed until: 2024-11-15
Embargoed until: 2024-11-15
Volume
4
Pagination
755 - 758
Publisher
DOI
10.1038/s43587-024-00634-y
Journal
Nat Aging
Issue
Metadata
Show full item recordAbstract
Aging-related DNA methylation changes are numerous. Their precise measurement has opened new avenues to explore aging-related disease pathology, including the construction of chronological and biological age predictors (termed DNA methylation ‘clocks’). Three studies investigate the substantial stochastic contribution to these epigenetic changes and further our understanding of aging biology, as well as of these predictors.