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Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits.
Over the last decade, genome-wide association studies (GWAS) have propelled the discovery of thousands of loci associated with complex diseases. The focus is now turning toward the function of these association signals, ...
Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths.
BACKGROUND: Although stillbirth is a significant health problem worldwide, the definitive cause of death remains elusive in many cases, despite detailed autopsy. In this study of partly explained and unexplained stillbirths, ...