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    Munroe, PB (160)
    Warren, HR (65)Caulfield, MJ (58)Samani, NJ (55)Hayward, C (54)Gudnason, V (49)Rotter, JI (48)Smith, AV (45)van der Harst, P (45)Rudan, I (43)... View MoreSubjectgenome-wide association study (8)genetics (7)blood pressure (6)GWAS (6)Humans (5)hypertension (5)meta-analysis (5)epidemiology (4)artificial intelligence (3)atrial fibrillation (3)... View MoreDate Issued2020 - 2023 (64)2010 - 2019 (93)2008 - 2009 (3)
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    Emerging applications of genome-editing technology to examine functionality of GWAS-associated variants for complex traits. 

    Smith, AJP; Deloukas, P; Munroe, PB (2018-07-01)
    Over the last decade, genome-wide association studies (GWAS) have propelled the discovery of thousands of loci associated with complex diseases. The focus is now turning toward the function of these association signals, ...
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    Genetic Evidence for a Normal-Weight "Metabolically Obese" Phenotype Linking Insulin Resistance, Hypertension, Coronary Artery Disease, and Type 2 Diabetes 

    Yaghootkar, H; Scott, RA; White, CC; Zhang, W; Speliotes, E; Munroe, PB; Ehret, GB; Bis, JC; Fox, CS; Walker, M;... (2014-12)
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    Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths. 

    Munroe, PB; Addison, S; Abrams, DJ; Sebire, NJ; Cartwright, J; Donaldson, I; Cohen, MM; Mein, C; Tinker, A; Harmer, SC;... (2018-01)
    BACKGROUND: Although stillbirth is a significant health problem worldwide, the definitive cause of death remains elusive in many cases, despite detailed autopsy. In this study of partly explained and unexplained stillbirths, ...
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    Association Between Ambient Air Pollution and Cardiac Morpho-Functional Phenotypes: Insights From the UK Biobank Population Imaging Study. 

    Aung, N; Sanghvi, MM; Zemrak, F; Lee, AM; Cooper, JA; Paiva, JM; Thomson, RJ; Fung, K; Khanji, MY; Lukaschuk, E;... (2018-11-13)
    Background: Exposure to ambient air pollution is strongly associated with increased cardiovascular morbidity and mortality. Little is known about the influence of air pollutants on cardiac structure and function. We aim ...
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    Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system. 

    Ramírez, J; Duijvenboden, SV; Ntalla, I; Mifsud, B; Warren, HR; Tzanis, E; Orini, M; Tinker, A; Lambiase, PD; Munroe, PB (2018-05-16)
    Impaired capacity to increase heart rate (HR) during exercise (ΔHRex), and a reduced rate of recovery post-exercise (ΔHRrec) are associated with higher cardiovascular mortality rates. Currently, the genetic basis of both ...
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    Quantifying the extent to which index event biases influence large genetic association studies 

    Yaghootkar, H; Bancks, MP; Jones, SE; McDaid, A; Beaumont, R; Donnelly, L; Wood, AR; Campbell, A; Tyrrell, J; Hocking, LJ;... (2017-03-01)
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    Testing the role of predicted gene knockouts in human anthropometric trait variation 

    Lessard, S; Manning, AK; Low-Kam, C; Auer, PL; Giri, A; Graff, M; Schurmann, C; Yaghootkar, H; Luan, J; Esko, T;... (2016-05-15)
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    Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits 

    Evangelou, E; Warren, HR; Mosen-Ansorena, D; Mifsu, B; Pazoki, R; Gao, H; Ntritsos, G; Dimou, N; Cabrer, CP; Karaman, I;... (2018-10)
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    Trans-ancestry meta-analyses identify rare and common variants associated with blood pressure and hypertension 

    Surendran, P; Drenos, F; Young, R; Warren, H; Cook, JP; Manning, AK; Grarup, N; Sim, X; Barnes, DR; Witkowska, K;... (2016-10)
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    Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits 

    Randall, JC; Winkler, TW; Kutalik, Z; Berndt, SI; Jackson, AU; Monda, KL; Kilpelaeinen, TO; Esko, T; Maegi, R; Li, S;... (2013-06)
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