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Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study.

Wijeysundera, DN; Pearse, RM; Shulman, MA; Abbott, TEF; Torres, E; Ambosta, A; Croal, BL; Granton, JT; Thorpe, KE; Grocott, MPW;... (2018-06-30)

BACKGROUND: Functional capacity is an important component of risk assessment for major surgery. Doctors' clinical subjective assessment of patients' functional capacity has uncertain accuracy. We did a study to compare ...

Cardiac vagal dysfunction and myocardial injury after non-cardiac surgery: a planned secondary analysis of the measurement of Exercise Tolerance before surgery study.

Abbott, TEF; Pearse, RM; Cuthbertson, BH; Wijeysundera, DN; Ackland, GL; METS study investigators (2019-02)

BACKGROUND: The aetiology of perioperative myocardial injury is poorly understood and not clearly linked to pre-existing cardiovascular disease. We hypothesised that loss of cardioprotective vagal tone [defined by impaired ...

Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non-cardiac surgery

Ackland, GL; Abbott, TEF; Cain, D; Edwards, MR; Sultan, P; Karmali, SN; Fowler, AJ; Whittle, JR; MacDonald, NJ; Reyes, A;... (2019-02)

Improving care at scale: process evaluation of a multi-component quality improvement intervention to reduce mortality after emergency abdominal surgery (EPOCH trial).

Stephens, TJ; Peden, CJ; Pearse, RM; Shaw, SE; Abbott, TEF; Jones, EL; Kocman, D; Martin, G; EPOCH trial group (2018-11-13)

BACKGROUND: Improving the quality and safety of perioperative care is a global priority. The Enhanced Peri-Operative Care for High-risk patients (EPOCH) trial was a stepped-wedge cluster randomised trial of a quality ...

Measurement of Exercise Tolerance before Surgery (METS) study: a protocol for an international multicentre prospective cohort study of cardiopulmonary exercise testing prior to major non-cardiac surgery

Wijeysundera, DN; Pearse, RM; Shulman, MA; Abbott, TEF; Torres, E; Croal, BL; Granton, JT; Thorpe, KE; Grocott, MPW; Farrington, C;... (2016)

The Prevention of Respiratory Insufficiency after Surgical Management (PRISM) Trial Report of the protocol for a pragmatic randomized controlled trial of CPAP to prevent respiratory complications and improve survival following major abdominal surgery

Pearse, RM; Abbott, TEF; Haslop, R; Ahmad, T; Kahan, BC; Filipini, C; Rhodes, A; Ranieri, M (2017-02)

Frequency of surgical treatment and related hospital procedures in the UK: a national ecological study using hospital episode statistics

Abbott, TEF; Fowler, AJ; Dobbs, TD; Harrison, EM; Gillies, MA; Pearse, RM (2017-08)

Global patient outcomes after elective surgery: prospective cohort study in 27 low-, middle- and high-income countries The International Surgical Outcomes Study group

Ahmad, T; Bouwman, RA; Grigoras, I; Aldecoa, C; Hofer, C; Hoeft, A; Holt, P; Fleisher, LA; Buhre, W; Pearse, RM;... (2016-11)

The ASOS Surgical Risk Calculator: development and validation of a tool for identifying African surgical patients at risk of severe postoperative complications

Kluyts, H-L; le Manach, Y; Munlemvo, DM; Madzimbamuto, F; Basenero, A; Coulibaly, Y; Rakotoarison, S; Gobin, V; Samateh, AL; Chaibou, MS;... (Elsevier, 2018-09-17)

Background: The African Surgical Outcomes Study (ASOS) showed that surgical patients in Africa have a mortality twice the global average. Existing risk assessment tools are not valid for use in this population because the ...

Evidence-based medicine: the clue is in the name.

Moppett, IK; Pearse, RM (2017-12-01)

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