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Inhibition of cardiac potassium currents by oxidation-activated protein kinase A contributes to early afterdepolarizations in the heart

Trum, M; Islam, MMT; Lebek, S; Baier, M; Hegner, P; Eaton, P; Maier, LS; Wagner, S (2020-12)

Oxidation of Protein Kinase A Regulatory Subunit PKARI alpha Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release

Simon, JN; Vrellaku, B; Monterisi, S; Chu, SM; Rawlings, N; Lomas, O; Marchal, GA; Waithe, D; Syeda, F; Gajendragadkar, PR (2021-02-02)

Enhanced Heart Failure in Redox-Dead Cys17Ser PKARI alpha Knock-In Mice

Islam, MMT; Tarnowski, D; Zhang, M; Trum, M; Lebek, S; Mustroph, J; Daniel, H; Moellencamp, J; Pabel, S; Sossalla, S (2021-10-05)

POS0441 IN-DEPTH ANALYSIS OF Axl AND MerTK EXPRESSION PATTERNS AND REGULATION BY BIOLOGIC TREATMENTS IN RHEUMATOID ARTHRITIS

Nerviani, A; Boutet, MA; Ghirardi, GM; Goldmann, K; Sciacca, E; Rivellese, F; Pontarini, E; Caliste, M; Prediletto, E; Bombardieri, M (2022-05-23)

Tofacitinib Decreases Autophagy of Fibroblast-Like Synoviocytes From Rheumatoid Arthritis Patients

Vomero, M; Caliste, M; Barbati, C; Speziali, M; Celia, AI; Ucci, F; Ciancarella, C; Putro, E; Colasanti, T; Buoncuore, G (2022-03-03)

Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression

Meednu, N; Rangel-Moreno, J; Zhang, F; Escalera-Rivera, K; Corsiero, E; Prediletto, E; DiCarlo, E; Goodman, S; Donlin, LT; Raychauduri, S (2022-05-03)

POS0399 CHARACTERIZATION OF HSP60, A STROMAL-DERIVED AUTOANTIGEN, RECOGNIZED BY RA SYNOVIAL RECOMBINANT MONOCLONAL ANTIBODIES

Corsiero, E; Caliste, M; Jagemann, L; Prediletto, E; Pitzalis, C; Bombardieri, M (2022-05-23)

POS0439 STROMAL B-CELL CROSSTALK PROMOTES THE ESTABLISHMENT OF SYNOVIAL B CELL NICHES THROUGH THE SELECTION, ACTIVATION OF NATURALLY OCCURRING EBV+ B CELLS

Caliste, M; Prediletto, E; Corsiero, E; Jagemann, L; Pitzalis, C; Bombardieri, M (2022-05-23)

Single cell analysis of RA synovial B cells reveals a dynamic spectrum of ectopic lymphoid B cell activation and hypermutation characterized by NR4A nuclear receptor expression

Meednu, N; Rangel-Moreno, J; Zhang, F; Escalera-Rivera, K; Corsiero, E; Prediletto, E; DiCarlo, E; Goodman, S; Donlin, L; Raychauduri, S (2021-05-16)

<h4>ABSTRACT</h4> Ectopic lymphoid structures (ELS) can develop in rheumatoid arthritis (RA) synovial tissue, but the precise pathways of B cell activation and selection are not well understood. Here, we identified a unique ...

Advancements in nanomedicines for the detection and treatment of diabetic kidney disease

Tillman, L; Tabish, TA; Kamaly, N; Moss, P; El-briri, A; Thiemermann, C; Pranjol, ZI; Yaqoob, MM (2022-06-01)

Redox-dependent internalization of the purinergic P2Y(6) receptor limits colitis progression

Nishiyama, K; Nishimura, A; Shimoda, K; Tanaka, T; Kato, Y; Shibata, T; Tanaka, H; Kurose, H; Azuma, Y-T; Ihara, H (2022-01-11)

Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure

Reynolds, CJ; Pade, C; Gibbons, JM; Otter, AD; Lin, K-M; Sandoval, DM; Pieper, FP; Butler, DK; Liu, S; Joy, G (2022-07-15)

The reaction of hydropersulfides (RSSH) with S-nitrosothiols (RS-NO) and the biological/physiological implications

Zarenkiewicz, J; Perez-Ternero, C; Kojasoy, V; McGinity, C; Khodade, VS; Lin, J; Tantillo, DJ; Toscano, JP; Hobbs, AJ; Fukuto, JM (2022-08-01)

Estimation of biological heart age using cardiovascular magnetic resonance radiomics.

Raisi-Estabragh, Z; Salih, A; Gkontra, P; Atehortúa, A; Radeva, P; Boscolo Galazzo, I; Menegaz, G; Harvey, NC; Lekadir, K; Petersen, SE (2022-07-27)

We developed a novel interpretable biological heart age estimation model using cardiovascular magnetic resonance radiomics measures of ventricular shape and myocardial character. We included 29,996 UK Biobank participants ...

Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I

Kamynina, A; Guttzeit, S; Eaton, P; Cuello, F (2022-05)

Heart failure-emerging roles for the mitochondrial pyruvate carrier

Fernandez-Caggiano, M; Eaton, P (2021-04)

Role of plasma extracellular vesicles in prediction of cardiovascular risk and alterations in response to statin therapy in hypertensive patients

Oggero, S; Godec, T; van Gorp, R; Pinto, LA; Schurgers, JL; Reutelingsperger, C; Sever, P; Norling, LV; Perretti, M; Gupta, A (2022-08)

William Harvey Research Institute: Recent submissions

Inhibition of cardiac potassium currents by oxidation-activated protein kinase A contributes to early afterdepolarizations in the heart

Oxidation of Protein Kinase A Regulatory Subunit PKARI alpha Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release

Enhanced Heart Failure in Redox-Dead Cys17Ser PKARI alpha Knock-In Mice

POS0441 IN-DEPTH ANALYSIS OF Axl AND MerTK EXPRESSION PATTERNS AND REGULATION BY BIOLOGIC TREATMENTS IN RHEUMATOID ARTHRITIS

Tofacitinib Decreases Autophagy of Fibroblast-Like Synoviocytes From Rheumatoid Arthritis Patients

Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression

POS0399 CHARACTERIZATION OF HSP60, A STROMAL-DERIVED AUTOANTIGEN, RECOGNIZED BY RA SYNOVIAL RECOMBINANT MONOCLONAL ANTIBODIES

POS0439 STROMAL B-CELL CROSSTALK PROMOTES THE ESTABLISHMENT OF SYNOVIAL B CELL NICHES THROUGH THE SELECTION, ACTIVATION OF NATURALLY OCCURRING EBV+ B CELLS

Single cell analysis of RA synovial B cells reveals a dynamic spectrum of ectopic lymphoid B cell activation and hypermutation characterized by NR4A nuclear receptor expression

Advancements in nanomedicines for the detection and treatment of diabetic kidney disease

Redox-dependent internalization of the purinergic P2Y(6) receptor limits colitis progression

Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure

The reaction of hydropersulfides (RSSH) with S-nitrosothiols (RS-NO) and the biological/physiological implications

Estimation of biological heart age using cardiovascular magnetic resonance radiomics.

Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I

Heart failure-emerging roles for the mitochondrial pyruvate carrier

Role of plasma extracellular vesicles in prediction of cardiovascular risk and alterations in response to statin therapy in hypertensive patients

Prescribing direct-acting oral anticoagulants - Mind the evidence gap

The impact of the COVID-19 pandemic on the delivery of primary percutaneous coronary intervention in STEMI.

Redox Regulation of Soluble Epoxide Hydrolase-Implications for Cardiovascular Health and Disease

William Harvey Research Institute: Recent submissions

Inhibition of cardiac potassium currents by oxidation-activated protein kinase A contributes to early afterdepolarizations in the heart ﻿

Oxidation of Protein Kinase A Regulatory Subunit PKARI alpha Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release ﻿

Enhanced Heart Failure in Redox-Dead Cys17Ser PKARI alpha Knock-In Mice ﻿

POS0441 IN-DEPTH ANALYSIS OF Axl AND MerTK EXPRESSION PATTERNS AND REGULATION BY BIOLOGIC TREATMENTS IN RHEUMATOID ARTHRITIS ﻿

Tofacitinib Decreases Autophagy of Fibroblast-Like Synoviocytes From Rheumatoid Arthritis Patients ﻿

Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression ﻿

POS0399 CHARACTERIZATION OF HSP60, A STROMAL-DERIVED AUTOANTIGEN, RECOGNIZED BY RA SYNOVIAL RECOMBINANT MONOCLONAL ANTIBODIES ﻿

POS0439 STROMAL B-CELL CROSSTALK PROMOTES THE ESTABLISHMENT OF SYNOVIAL B CELL NICHES THROUGH THE SELECTION, ACTIVATION OF NATURALLY OCCURRING EBV+ B CELLS ﻿

Single cell analysis of RA synovial B cells reveals a dynamic spectrum of ectopic lymphoid B cell activation and hypermutation characterized by NR4A nuclear receptor expression ﻿

Advancements in nanomedicines for the detection and treatment of diabetic kidney disease ﻿

Redox-dependent internalization of the purinergic P2Y(6) receptor limits colitis progression ﻿

Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure ﻿

The reaction of hydropersulfides (RSSH) with S-nitrosothiols (RS-NO) and the biological/physiological implications ﻿

Estimation of biological heart age using cardiovascular magnetic resonance radiomics. ﻿

Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I ﻿

Heart failure-emerging roles for the mitochondrial pyruvate carrier ﻿

Role of plasma extracellular vesicles in prediction of cardiovascular risk and alterations in response to statin therapy in hypertensive patients ﻿

Prescribing direct-acting oral anticoagulants - Mind the evidence gap ﻿

The impact of the COVID-19 pandemic on the delivery of primary percutaneous coronary intervention in STEMI. ﻿

Redox Regulation of Soluble Epoxide Hydrolase-Implications for Cardiovascular Health and Disease ﻿

Inhibition of cardiac potassium currents by oxidation-activated protein kinase A contributes to early afterdepolarizations in the heart

Oxidation of Protein Kinase A Regulatory Subunit PKARI alpha Protects Against Myocardial Ischemia-Reperfusion Injury by Inhibiting Lysosomal-Triggered Calcium Release

Enhanced Heart Failure in Redox-Dead Cys17Ser PKARI alpha Knock-In Mice

POS0441 IN-DEPTH ANALYSIS OF Axl AND MerTK EXPRESSION PATTERNS AND REGULATION BY BIOLOGIC TREATMENTS IN RHEUMATOID ARTHRITIS

Tofacitinib Decreases Autophagy of Fibroblast-Like Synoviocytes From Rheumatoid Arthritis Patients

Dynamic spectrum of ectopic lymphoid B cell activation and hypermutation in the RA synovium characterized by NR4A nuclear receptor expression

POS0399 CHARACTERIZATION OF HSP60, A STROMAL-DERIVED AUTOANTIGEN, RECOGNIZED BY RA SYNOVIAL RECOMBINANT MONOCLONAL ANTIBODIES

POS0439 STROMAL B-CELL CROSSTALK PROMOTES THE ESTABLISHMENT OF SYNOVIAL B CELL NICHES THROUGH THE SELECTION, ACTIVATION OF NATURALLY OCCURRING EBV+ B CELLS

Single cell analysis of RA synovial B cells reveals a dynamic spectrum of ectopic lymphoid B cell activation and hypermutation characterized by NR4A nuclear receptor expression

Advancements in nanomedicines for the detection and treatment of diabetic kidney disease

Redox-dependent internalization of the purinergic P2Y(6) receptor limits colitis progression

Immune boosting by B.1.1.529 (Omicron) depends on previous SARS-CoV-2 exposure

The reaction of hydropersulfides (RSSH) with S-nitrosothiols (RS-NO) and the biological/physiological implications

Estimation of biological heart age using cardiovascular magnetic resonance radiomics.

Nitroxyl Donor CXL-1020 Lowers Blood Pressure by Targeting C195 in Cyclic Guanosine-3',5'-Monophosphate-Dependent Protein Kinase I

Heart failure-emerging roles for the mitochondrial pyruvate carrier

Role of plasma extracellular vesicles in prediction of cardiovascular risk and alterations in response to statin therapy in hypertensive patients

Prescribing direct-acting oral anticoagulants - Mind the evidence gap

The impact of the COVID-19 pandemic on the delivery of primary percutaneous coronary intervention in STEMI.

Redox Regulation of Soluble Epoxide Hydrolase-Implications for Cardiovascular Health and Disease