RSS 1.0Endocrinology
Browse by
Recent Submissions
-
PHENOTYPIC SPECTRUM AND RESPONSES TO RECOMBINANT HUMAN IGF1 (rhIGF1) THERAPY IN PATIENTS WITH HOMOZYGOUS INTRONIC PSEUDOEXON GROWTH HORMONE RECEPTOR MUTATION.
(2018-03-02)BACKGROUND: Patients with homozygous intronic pseudoexon GH receptor(GHR) mutations(6Ψ) have growth hormone Insensitivity(GHI) (growth failure, IGF1 deficiency and normal/elevated serum GH). We report 9 patients in addition ... -
Multi-chaperone function modulation and association with cytoskeletal proteins are key features of the function of AIP in the pituitary gland
(Impact Journals, 2018-01-11)© Hernández-Ramírez et al. Despite the well-recognized role of loss-of-function mutations of the aryl hydrocarbon receptor interacting protein gene (AIP) predisposing to pituitary adenomas, the pituitary-specific function ... -
AIP and the somatostatin system in pituitary tumours.
(2017-12-01)Classic somatostatin analogues aimed at somatostatin receptor type 2, such as octreotide and lanreotide, represent the mainstay of medical treatment for acromegaly. These agents have the potential to decrease hormone ... -
Expression of progenitor markers is associated with the functionality of a bioartificial adrenal cortex.
(Public Library of Science (PLoS), 2018-03-29)Encapsulation of primary bovine adrenocortical cells in alginate is an efficacious model of a bioartificial adrenal cortex. Such a bioartificial adrenal cortex can be used for the restoration of lost adrenal function in ... -
De novo HNF1 homeobox B mutation as a cause for chronic, treatment-resistant hypomagnesaemia.
(Bioscientifica Ltd, 2018-03-21)29-year-old female presenting with an 8-year history of unexplained hypomagnesaemia, which was severe enough to warrant intermittent inpatient admission for intravenous magnesium. Urinary magnesium was inappropriately ...
