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Lycopene reduces ovarian tumor growth and intraperitoneal metastatic load.
(e-Century Publishing, 2017-06-15)Mutagens like oxidants cause lesions in the DNA of ovarian and fallopian tube epithelial cells, resulting in neoplastic transformation. Reduced exposure of surface epithelia to oxidative stress may prevent the onset or ... -
Use multi-omics platforms for comprehensive assessment of the mechanism of action of kallikreinrelated peptidase 4 (KLK4) in the prostate tumour microenvironment
(Wiley, 2016-08)Abstracts from the 17th Asia-Pacific Prostate Cancer Conference 2016, Australia, 31 August–3 September 2016 -
A humanised tissue-engineered bone model allows species-specific breast cancer-related bone metastasis in vivo.
(Wiley, 2017-07-17)Bone metastases frequently occur in the advanced stages of breast cancer. At this stage, the disease is deemed incurable. To date, the mechanisms of breast cancer-related metastasis to bone are poorly understood. This may ... -
CRISPR/Cas9-Mediated Trp53 and Brca2 Knockout to Generate Improved Murine Models of Ovarian High-Grade Serous Carcinoma.
(American Association for Cancer Research, 2016-08-16)There is a need for transplantable murine models of ovarian high-grade serous carcinoma (HGSC) with regard to mutations in the human disease to assist investigations of the relationships between tumor genotype, chemotherapy ...
