• Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion 

  Murray, ER; Menezes, S; Henry, JC; Williams, JL; Alba-Castellon, L; Baskaran, P; Quetier, I; Desai, A; Marshall, JJT; Rosewell, I (2022-01-25)

• Targeting the lysine-specific demethylase 1 rewires kinase networks and primes leukemia cells for kinase inhibitor treatment. 

  Pedicona, F; Casado, P; Hijazi, M; Gribben, JG; Rouault-Pierre, K; Cutillas, PR (2022-04-19)

  Most tumor types either fail to respond or become resistant to kinase inhibitors, often because of compensatory prosurvival pathways in the cancer cell's broader signaling circuitry. Here, we found that intrinsic resistance ...

• Shining light on dark selection in healthy human tissues 

  Werner, B (2021-11)

• Carbon dating cancer: defining the chronology of metastatic progression in colorectal cancer. 

  Lote, H; Spiteri, I; Ermini, L; Vatsiou, A; Roy, A; McDonald, A; Maka, N; Balsitis, M; Bose, N; Simbolo, M (2017-06-01)

  Background: Patients often ask oncologists how long a cancer has been present before causing symptoms or spreading to other organs. The evolutionary trajectory of cancers can be defined using phylogenetic approaches but ...

• CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation 

  Lawson, H; van de Lagemaat, LN; Barile, M; Tavosanis, A; Durko, J; Villacreces, A; Bellani, A; Mapperley, C; Georges, E; Martins-Costa, C (2021-11-09)

• Longitudinal profiling of circulating tumour DNA for tracking tumour dynamics in pancreatic cancer. 

  Sivapalan, L; Thorn, GJ; Gadaleta, E; Kocher, HM; Ross-Adams, H; Chelala, C (2022-04-07)

  BACKGROUND: The utility of circulating tumour DNA (ctDNA) for longitudinal tumour monitoring in pancreatic ductal adenocarcinoma (PDAC) has not been explored beyond mutations in the KRAS proto-oncogene. Here, we aimed to ...

• Impact of COVID-19 in patients with lymphoid malignancies. 

  Riches, JC (2021-05-25)

  The first cases of coronavirus disease 2019 (COVID-19) were detected in Wuhan, China, in December 2019. Since this time a concerted global effort of research and observational data gathering has meant that a great deal has ...

• Alteration of ribosome function upon 5-fluorouracil treatment favors cancer cell drug-tolerance. 

  Therizols, G; Bash-Imam, Z; Panthu, B; Machon, C; Vincent, A; Ripoll, J; Nait-Slimane, S; Chalabi-Dchar, M; Gaucherot, A; Garcia, M (2022-01-10)

  Mechanisms of drug-tolerance remain poorly understood and have been linked to genomic but also to non-genomic processes. 5-fluorouracil (5-FU), the most widely used chemotherapy in oncology is associated with resistance. ...

• Chemotherapy Induces Tumor-Associated Macrophages that Aid Adaptive Immune Responses in Ovarian Cancer 

  Heath, O; Berlato, C; Maniati, E; Lakhani, A; Pegrum, C; Kotantaki, P; Elorbany, S; Bohm, S; Barry, ST; Annibaldi, A (2021-06-01)

• Impact of Youth and Adult Informal Science Educators on Youth Learning at Exhibits 

  McGuire, L; Hoffman, AJ; Mulvey, KL; Winterbottom, M; Balkwill, F; Burns, KP; Chatton, M; Drews, M; Eaves, N; Fields, GE (2022-01-01)

  The impact of educators in informal science learning sites (ISLS) remains understudied from the perspective of youth visitors. Less is known about whether engagement with educators differs based on the age and gender of ...

• TGFBI Production by Macrophages Contributes to an Immunosuppressive Microenvironment in Ovarian Cancer 

  Lecker, LSM; Berlato, C; Maniati, E; Delaine-Smith, R; Pearce, OMT; Heath, O; Nichols, SJ; Trevisan, C; Novak, M; McDermott, J (2021-11)

• Stromal Cells Promote Matrix Deposition, Remodelling and an Immunosuppressive Tumour Microenvironment in a 3D Model of Colon Cancer 

  Leonard, NA; Reidy, E; Thompson, K; McDermott, E; Peerani, E; Tomas Bort, E; Balkwill, FR; Loessner, D; Ryan, AE (2021-12)

• P032. The role of P-cadherin in early breast cancer risk stratification 

  Allen, N; Allen, M; Gomm, J; Jones, L; Don't know (2021-05-01)

• P020. Defining molecular signatures to personalise management of patients with early breast cancer 

  Allen, N; Allen, M; Gomm, J; Nelan, R; Nagano, A; Chelala, C; Jones, L (2021-05-01)

• The DNA methylome of cervical cells can predict the presence of ovarian cancer 

  Barrett, JE; Jones, A; Evans, I; Reisel, D; Herzog, C; Chindera, K; Kristiansen, M; Leavy, OC; Manchanda, R; Bjorge, L (2022-02-01)

• Improved Immunotherapy Efficacy by Vascular Modulation 

  Newport, EL; Rita Pedrosa, A; Njegic, A; Hodivala-Dilke, KM; Munoz-Felix, JM (2021-10)

• A systemically deliverable Vaccinia virus with increased capacity for intertumoral and intratumoral spread effectively treats pancreatic cancer 

  Marelli, G; Dunmall, LSC; Yuan, M; Di Gioia, C; Miao, J; Cheng, Z; Zhang, Z; Liu, P; Ahmed, J; Gangeswaran, R (2021)

• COVID-19 in patients with hepatobiliary and pancreatic diseases: a single-centre cross-sectional study in East London 

  Ullah, AZMD; Sivapalan, L; Kocher, HM; Chelala, C (2021)

• Impact of SARS-CoV-2 pandemic on pancreatic cancer services and treatment pathways: United Kingdom experience 

  McKay, SC; Pathak, S; Wilkin, RJW; Kamarajah, SK; Wigmore, SJ; Rees, J; Dunne, DFJ; Garcea, G; Ahmad, J; Carino, NDL (2021-11)

• Temporality of clinical factors associated with pancreatic cancer: a case-control study using linked electronic health records 

  Ullah, AZMD; Stasinos, K; Chelala, C; Kocher, HM (2021-11-27)

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