Barts Cancer Institute

The molecular pathogenesis of the NUP98-HOXA9 fusion protein in Acute Myeloid Leukemia

DEL RIO MACHIN, A; Fitzgibbon, J (Nature Publishing Group, 17-06-20)
Changing the Risk Threshold for Surgical Prevention of Ovarian Cancer

MANCHANDA, R; Legood, R; Antoniou, AC; Pearce, L; Menon, U (Wiley, 2017-05-26)
ONCOGENE-EXPRESSING SENESCENT MELANOCYTES UPREGULATE MHC CLASS II, A CANDIDATE MELANOMA SUPPRESSOR FUNCTION

BRAUNS, A (Elsevier, 2017-06-22)

On acquisition of an oncogenic mutation, primary human and mouse cells can enter oncogene-induced senescence (OIS). OIS is characterized by a stable proliferation arrest and secretion of pro-inflammatory cytokines and ...
A rapid method for combined analysis of common and rare variants at the level of a region, gene, or pathway.

Curtis, D (2012-07-24)

Previously described methods for the combined analysis of common and rare variants have disadvantages such as requiring an arbitrary classification of variants or permutation testing to assess statistical significance. ...
Optimization and Evaluation of a Novel Size Based Circulating Tumor Cell Isolation System.

Xu, L; Mao, X; Imrali, A; Syed, F; Mutsvangwa, K; Berney, D; Cathcart, P; Hines, J; Shamash, J; Lu, Y-J (2015-09-23)

Isolation of circulating tumor cells (CTCs) from peripheral blood has the potential to provide a far easier "liquid biopsy" than tumor tissue biopsies, to monitor tumor cell populations during disease progression and in ...

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