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    Author
    Graham, TA (67)
    Sottoriva, A (20)Baker, A-M (14)Wright, NA (14)Williams, MJ (10)Jansen, M (9)Barnes, CP (8)Martinez, P (8)Rodriguez-Justo, M (8)Temko, D (8)... View MoreSubjectcolorectal cancer (4)Tumor heterogeneity (3)Cancer (2)cancer (2)Cancer evolution (2)cancer evolution (2)Colorectal cancer (2)genomics (2)gradualism (2)Heterogeneity (2)... View MoreDate Issued2021 (5)2020 (12)2019 (9)2018 (12)2017 (12)2016 (9)2015 (5)2014 (1)2013 (2)
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    A HIF-LIMD1 negative feedback mechanism mitigates the pro-tumorigenic effects of hypoxia. 

    Foxler, DE; Bridge, KS; Foster, JG; Grevitt, P; Curry, S; Shah, KM; Davidson, KM; Nagano, A; Gadaleta, E; Rhys, HI;... (2018-08)
    The adaptive cellular response to low oxygen tensions is mediated by the hypoxia-inducible factors (HIFs), a family of heterodimeric transcription factors composed of HIF-α and HIF-β subunits. Prolonged HIF expression is ...
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    Spatial Sampling in Barrett's Oesophagus Shows Clonal Evolution of Oesophageal Adenocarcinoma from Metaplastic Non-Goblet Columnar Epithelium 

    Jansen, M; McDonald, SA; Lavery, D; Wright, NA; Martinez, P; Graham, TA; Gay, LJ (2015-09)
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    Characterization of LGR5 stem cells in colorectal adenomas and carcinomas 

    Baker, A-M; Graham, TA; Elia, G; Wright, NA; Rodriguez-Justo, M (2015-03-02)
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    Evolution of oesophageal adenocarcinoma from metaplastic columnar epithelium without goblet cells in Barrett's oesophagus 

    Lavery, DL; Martinez, P; Gay, LJ; Cereser, B; Novelli, MR; Rodriguez-Justo, M; Meijer, SL; Graham, TA; McDonald, SAC; Wright, NA;... (2016-06)
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    PIK3CA mutations are common in lobular carcinoma in situ, but are not a biomarker of progression 

    Shah, V; Nowinski, S; Levi, D; Shinomiya, I; Chaabouni, NKE; Gillett, C; Grigoriadis, A; Graham, TA; Roylance, R; Simpson, MA;... (2017-01-17)
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    Between-region genetic divergence reflects the mode and tempo of tumor evolution 

    Sun, R; Hu, Z; Sottoriva, A; Graham, TA; Harpak, A; Ma, Z; Fischer, JM; Shibata, D; Curtis, C (2017-07)
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    New paradigms in clonal evolution: punctuated equilibrium in cancer 

    Cross, WCH; Graham, TA; Wright, NA (2016-10)
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    From Colitis to Cancer: An Evolutionary Trajectory That Merges Maths and Biology 

    Al Bakir, I; Curtius, K; Graham, TA (2018-10-16)
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    Forty-Year Analysis of Colonoscopic Surveillance Program for Neoplasia in Ulcerative Colitis: An Updated Overview 

    Choi, C-HR; Rutter, MD; Askari, A; Lee, GH; Warusavitarne, J; Moorghen, M; Thomas-Gibson, S; Saunders, BP; Graham, TA; Hart, AL (2015-07)
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    Clonal evolution of colorectal cancer in IBD 

    Choi, C-HR; Al Bakir, I; Hart, AL; Graham, TA (2017-04)
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