Centre for Cell and Molecular Biology
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Recent Submissions
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An mRNA processing pathway suppresses metastasis by governing translational control from the nucleus
(Nature Research, 2023-05-08)Cancer cells often co-opt post-transcriptional regulatory mechanisms to achieve pathologic expression of gene networks that drive metastasis. Translational control is a major regulatory hub in oncogenesis; however, its ... -
Understanding and managing the cardiovascular risks of androgen deprivation therapy for prostate cancer
(Nature Research, 2022-10-24) -
Developing and centralising a nurse-led local anaesthetic transperineal biopsy service during COVID.
(Wiley, 2023-05-31)INTRODUCTION: Transperineal (TP) biopsy has recently replaced the transrectal ultrasound (TRUS) approach as the ideal method of biopsy in the United Kingdom with growing trends to adopt. To minimise transmission of COVID-19 ... -
The potential of using circulating tumour cells and their gene expression to predict docetaxel response in metastatic prostate cancer
(Frontiers Media, 2023-01-16)Background: Docetaxel improves overall survival (OS) in castration-resistant prostate cancer (PCa) (CRPC) and metastatic hormone-sensitive PCa (mHSPC). However, not all patients respond due to inherent and/or acquired ... -
Feasibility of aspirin and/or vitamin D3 for men with prostate cancer on active surveillance with Prolaris® testing.
(2022-11)OBJECTIVES: To test the feasibility of a randomised controlled trial (RCT) of aspirin and/or vitamin D3 in active surveillance (AS) low/favourable intermediate risk prostate cancer (PCa) patients with Prolaris® testing. ...