Recent Submissions

  • Catch my drift? Making sense of genomic intra-tumour heterogeneity. 

    Sottoriva, A; Barnes, CP; Graham, TA (Elsevier/Science Direct, 2017-01-07)
    The cancer genome is shaped by three components of the evolutionary process: mutation, selection and drift. While many studies have focused on the first two components, the role of drift in cancer evolution has received ...
  • The Gastric Epithelium: Slow Starter in the Stem Cell/Lineage Specification Stakes? 

    Wright, N (Elsevier/Science Direct, 2016-07-26)
    Stem cell dynamics and lineage specification form the basis of the understanding of the generation of metaplastic and neoplastic states in the gut. Although our knowledge in the intestine has raced ahead, the stomach lags ...
  • Multipotent Basal Stem Cells, Maintained in Localized Proximal Niches, Support Directed Long-Ranging Epithelial Flows in Human Prostates. 

    Moad, M; Hannezo, E; Buczacki, SJ; Wilson, L; El-Sherif, A; Sims, D; Pickard, R; Wright, NA; Williamson, SC; Turnbull, DM;... (Elsevier/Science Direct, 2017-08-15)
    Sporadic mitochondrial DNA mutations serve as clonal marks providing access to the identity and lineage potential of stem cells within human tissues. By combining quantitative clonal mapping with 3D reconstruction of adult ...
  • Stromal SPOCK1 supports invasive pancreatic cancer growth. 

    Veenstra, VL; Damhofer, H; Waasdorp, C; Steins, A; Kocher, HM; Medema, JP; van Laarhoven, HW; Bijlsma, MF (Wiley Open Access, 2017-06-05)
    Pancreatic ductal adenocarcinoma (PDAC) is marked by an abundant stromal deposition. This stroma is suspected to harbor both tumor-promoting and tumor-suppressing properties. This is underscored by the disappointing results ...
  • Role of laparoscopy in hepatobiliary malignancies. 

    Arumugam, P; Balarajah, V; Watt, J; Abraham, AT; Bhattacharya, S; Kocher, HM (Medknow Publications, 2016-04)
    The many benefits of laparoscopy, including smaller incision, reduced length of hospital stay and more rapid return to normal function, have seen its popularity grow in recent years. With concurrent improvements in ...
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