Now showing items 1-10 of 18
Organotypic modelling as a means of investigating epithelial-stromal interactions during tumourigenesis.
The advent of co-culture approaches has allowed researchers to more accurately model the behaviour of epithelial cells in cell culture studies. The initial work on epidermal modelling allowed the development of reconstituted ...
beta(3)A-integrin downregulates the urokinase-type plasminogen activator receptor (u-PAR) through a PEA3/ets transcriptional silencing element in the u-PAR promoter
(American Society for Microbiology, 2001-03-15)
Migration of cells requires interactions with the extracellular matrix mediated, in part, by integrins, proteases, and their receptors. Previous studies have shown that b3-integrin interacts with the urokinase-type plasminogen ...