• Lamin B1 regulates somatic mutations and progression of B-cell malignancies 

  Klymenko, T; Bloehdorn, J; Bahlo, J; Robrecht, S; Akylzhanova, G; Cox, K; Estenfelder, S; Wang, J; Edelmann, J; Strefford, JC (2018-02)

• Transmission of diffuse large B cell lymphoma by an allogeneic stem-cell transplant. 

  Araf, S; Wang, J; Ashton-Key, M; Korfi, K; Di Bella, D; Rio-Machin, A; Odabashian, M; Foria, V; Du, M-Q; Cucco, F (2018-07-05)

• Infusion of Alloanergized Donor Lymphocytes after CD34-selected Haploidentical Myeloablative Hematopoietic Stem Cell Transplantation. 

  Davies, JK; Brennan, LL; Wingard, JR; Cogle, CR; Kapoor, N; Shah, AJ; Dey, BR; Spitzer, TR; de Lima, M; Cooper, LJ (2018-09-01)

  Purpose: Allogeneic hematopoietic stem-cell transplantation (HSCT) is a curative treatment for many hematologic cancers. Use of haploidentical (mismatched) donors increases HSCT availability but is limited by severe ...

• GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML. 

  Al Seraihi, AF; Rio-Machin, A; Tawana, K; Bödör, C; Wang, J; Nagano, A; Heward, JA; Iqbal, S; Best, S; Lea, N (2018-04-19)

• Randomized comparison of liposomal amphotericin B versus placebo to prevent invasive mycoses in acute lymphoblastic leukaemia 

  Cornely, OA; Leguay, T; Maertens, J; Vehreschild, MJGT; Anagnostopoulos, A; Castagnola, C; Verga, L; Rieger, C; Kondakci, M; Haerter, G (2017-08)

• Predicting early relapse in follicular lymphoma: have we turned a corner? 

  Araf, S; Okosun, J; Fitzgibbon, J (2018-04)

• Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma 

  Araf, S; Wang, J; Korfi, K; Pangault, C; Kotsiou, E; Rio-Machin, A; Rahim, T; Heward, J; Clear, A; Iqbal, S (2018-05)

• Stabilization of the metaphase spindle by Cdc14 is required for recombinational DNA repair 

  Teresa Villoria, M; Ramos, F; Duenas, E; Faull, P; Rodriguez Cutillas, P; Clemente-Blanco, A (2017-01-04)

• Randomized phase 3 study of lenalidomide versus chlorambucil as first-line therapy for older patients with chronic lymphocytic leukemia (the ORIGIN trial) 

  Chanan-Khan, A; Egyed, M; Robak, T; Martinelli de Oliveira, FA; Echeveste, MA; Dolan, S; Desjardins, P; Blonski, JZ; Mei, J; Golany, N (2017-05)

• Integrated Molecular Meta-Analysis of 1,000 Pediatric High-Grade and Diffuse Intrinsic Pontine Glioma 

  Mackay, A; Burford, A; Carvalho, D; Izquierdo, E; Fazal-Salom, J; Taylor, KR; Bjerke, L; Clarke, M; Vinci, M; Nandhabalan, M (2017-10-09)

• Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia 

  Passaro, D; Di Tullio, A; Abarrategi, A; Rouault-Pierre, K; Foster, K; Ariza-McNaughton, L; Montaner, B; Chakravarty, P; Bhaw, L; Diana, G (2017-09-11)

• The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia. 

  Di Tullio, A; Rouault-Pierre, K; Abarrategi, A; Mian, S; Grey, W; Gribben, J; Stewart, A; Blackwood, E; Bonnet, D (2017-11-22)

  Cytarabine (AraC) represents the most effective single agent treatment for AML. Nevertheless, overriding AraC resistance in AML remains an unmet medical need. Here we show that the CHK1 inhibitor (CHK1i) GDC-0575 enhances ...

• The Ageing Brain: Effects on DNA Repair and DNA Methylation in Mice 

  Langie, SAS; Cameron, KM; Ficz, G; Oxley, D; Tomaszewski, B; Gorniak, JP; Maas, LM; Godschalk, RWL; van Schooten, FJ; Reik, W (2017-02)

• Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors 

  Horton, SJ; Giotopoulos, G; Yun, H; Vohra, S; Sheppard, O; Bashford-Rogers, R; Rashid, M; Clipson, A; Chan, W-I; Sasca, D (2017-09)

• Use of haploidentical stem cell transplantation continues to increase: the 2015 European Society for Blood and Marrow Transplant activity survey report 

  Passweg, JR; Baldomero, H; Bader, P; Bonini, C; Duarte, RF; Dufour, C; Gennery, A; Kroeger, N; Kuball, J; Lanza, F (2017-06)

• Hit-and-run epigenetic editing prevents senescence entry in primary breast cells from healthy donors. 

  Saunderson, EA; Stepper, P; Gomm, JJ; Hoa, L; Morgan, A; Allen, MD; Jones, JL; Gribben, JG; Jurkowski, TP; Ficz, G (2017-11-13)

  Aberrant promoter DNA hypermethylation is a hallmark of cancer; however, whether this is sufficient to drive cellular transformation is not clear. To investigate this question, we use a CRISPR-dCas9 epigenetic editing tool, ...

• ECIL-6 guidelines for the treatment of invasive candidiasis, aspergillosis and mucormycosis in leukemia and hematopoietic stem cell transplant patients 

  Tissot, F; Agrawal, S; Pagano, L; Petrikkos, G; Groll, AH; Skiada, A; Lass-Floerl, C; Calandra, T; Viscoli, C; Herbrecht, R (2017-03)

• Durable graft-versus-leukaemia effects without donor lymphocyte infusions - results of a phase II study of sequential T-replete allogeneic transplantation for high-risk acute myeloid leukaemia and myelodysplasia. 

  Davies, JK; Hassan, S; Sarker, S-J; Besley, C; Oakervee, H; Smith, M; Taussig, D; Gribben, JG; Cavenagh, JD (2018-02)

  Allogeneic haematopoietic stem-cell transplantation remains the only curative treatment for relapsed/refractory acute myeloid leukaemia (AML) and high-risk myelodysplasia but has previously been limited to patients who ...

• The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia 

  Rio-Machin, A; Gomez-Lopez, G; Munoz, J; Garcia-Martinez, F; Maiques-Diaz, A; Alvarez, S; Salgado, RN; Shrestha, M; Torres-Ruiz, R; Haferlach, C (2017-09)

• Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function 

  van Tuyn, J; Jaber-Hijazi, F; MacKenzie, D; Cole, JJ; Mann, E; Pawlikowski, JS; Rai, TS; Nelson, DM; McBryan, T; Ivanov, A (2017-10)

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