Barts Cancer Institute: Recent submissions
Now showing items 1-20 of 1423
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'Where is my gap': mechanisms underpinning PARP inhibitor sensitivity in cancer.
(Portland Press Ltd., 2025-02-10)The introduction of poly-ADP ribose polymerase (PARP) inhibitors (PARPi) has completely changed the treatment landscape of breast cancer susceptibility 1-2 (BRCA1-BRCA2)-mutant cancers and generated a new avenue of research ... -
The EHA Research Roadmap: Malignant Lymphoid Diseases
(Wolters Kluwer Health, Inc, 2022-05-19) -
Genetics of Transformed Follicular Lymphoma
(MDPI, 2022-10-01)Histological transformation (HT) to a more aggressive disease–mostly diffuse large B-cell lymphoma–is considered one of the most dismal events in the clinical course of follicular lymphoma (FL). Current knowledge has not ... -
Impact of positron emission tomography- computed tomography status on progression-free survival for relapsed follicular lymphoma patients undergoing autologous stem cell transplantation
(Ferrata Storti Foundation (Haematologica), 2022-05-19) -
Delays to Diagnosis of Peripheral T-Cell Lymphoma and Clinical Utility of Molecular Profiling: A UK Multicentre Real-World Study
(American Society of Hematology, 2024-11-05) -
Multi-Modal Analysis Reveals the Differences between Double Expressor and Non-Double Expressor Primary Central Nervous System Lymphomas
(American Society of Hematology, 2024-11-05) -
Prognostication and Treatment-Related Outcomes in Secondary Central Nervous System Involvement of Large B-Cell Lymphoma (SCNSL): Evidence from a Large International Cohort
(American Society of Hematology, 2024-11-05) -
Thyroid MALT lymphoma: self-harm to gain potential T-cell help
(Springer Nature, 2021-05-21) -
True-T - Improving T-cell response quantification with holistic artificial intelligence based prediction in immunohistochemistry images.
(Elsevier, 2023-12-01)The immune response associated with oncogenesis and potential oncological ther- apeutic interventions has dominated the field of cancer research over the last decade. T-cell lymphocytes in the tumor microenvironment are a ... -
Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression
(Springer Nature, 2021-03-17) -
Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment
(American Association for Cancer Research (AACR), 2022-05-16) -
ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning
(The Company of Biologists, 2022-07-12) -
Primary tumor-derived systemic nANGPTL4 inhibits metastasis
(Rockefeller University Press, 2022-10-21) -
Effects of senescence on the tumour microenvironment and response to therapy.
(Wiley, 2024-10-24)Cellular senescence is a state of durable cell arrest that has been identified both in vitro and in vivo. It is associated with profound changes in gene expression and a specific secretory profile that includes pro-inflammatory ... -
y Association of Low Tumor Endothelial Cell pY397-Focal Adhesion Kinase Expression With Survival in Patients With Neoadjuvant-Treated Locally Advanced Breast Cancer
(American Medical Association (AMA), 2020-10-27)