Browsing Barts Cancer Institute by Title

1009 – GENETIC IDENTIFICATION OF THE CELLULAR INTERACTOME THAT SUPPORTS T-CELL DEVELOPMENT IN THE THYMUS

Ganuza, M; Sanchez-Lanzas, R; Jimenez-Pompa, A; Efremova, M (Elsevier, 2023)

124P Acquired resistance to first-line chemo- and EGFRab-therapy in mCRC: Biopsy analysis of the iSCORE trial

Lane, R; Mencel, J; Turkes, F; Challoner, BR; McCafferty, N; Ntellas, P; Barber, LJ; Rana, I; Chen, H-C; Begum, R (Elsevier, 2024-06)

The 2019 Mathematical Oncology Roadmap.

Rockne, RC; Hawkins-Daarud, A; Swanson, KR; Sluka, JP; Glazier, JA; Macklin, P; Hormuth, D; Jarrett, AM; Lima, EABDF; Oden, J (IOP Publishing, 2019-04-16)

Whether the nom de guerre is Mathematical Oncology, Computational or Systems Biology, Theoretical Biology, Evolutionary Oncology, Bioinformatics, or simply Basic Science, there is no denying that mathematics continues to ...

208P ARB: Phase II window of opportunity study of preoperative treatment with enzalutamide in ER+ve and TNBC

Schmid, P; Gomez-Pardo, P; Wheatley, D; Roy, P; Krabisch, P; Thill, M; Ledwidge, S; Thompson, A; Macaskill, EJ; Viehstädt, N (Elsevier, 2021-09)

3009 – THERAPEUTIC TARGETING OF RNA DEGRADATION PATHWAYS- NEW AVENUES FOR INTERVENTION IN ACUTE MYELOID LEUKAEMIA

Mapperley, C; Lawson, H; Kabayama, Y; Georges, E; Azar, A; Van der Lagemaat, L; Paris, J; Morgan, M; Vernimmen, D; O'Carroll, D (Elsevier, 2022)

30P Immunological markers of pathological and clinical and outcomes in mismatch repair deficient (MMRd) colorectal cancer (CRC)

Challoner, BR; Slater, SC; Sansano, HB; Aresu, M; Bryant, A; Chen, H-C; Begum, R; Rana, T; Zhitkov, O; Leamon, B (Elsevier, 2024-06)

3D approaches to model the tumour microenvironment of pancreatic cancer

Loessner, D; Tomás-Bort, E; Kieler, M; Sharma, S; Candido, J (Ivyspring International Publisher, 2020-04-06)

In tumor engineering, 3D approaches are used to model components of the tumor microenvironment and to test new treatments. Pancreatic cancers are a cancer of substantial unmet need and survival rates are lower compared to ...

3D Functional Genomics Screens Identify CREBBP as a Targetable Driver in Aggressive Triple-Negative Breast Cancer

Peck, B; Bland, P; Mavrommati, I; Muirhead, G; Cottom, H; Wai, PT; Maguire, SL; Barker, HE; Morrison, E; Kriplani, D (American Association for Cancer Research (AACR), 2021-02-15)

3D Growth of Cancer Cells Elicits Sensitivity to Kinase Inhibitors but Not Lipid Metabolism Modifiers

Jones, DT; Valli, A; Haider, S; Zhang, Q; Smethurst, EA; Schug, ZT; Peck, B; Aboagye, EO; Critchlow, SE; Schulze, A (2019-02)

A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer

Carter, EP; Gopsill, JA; Gomm, JJ; Jones, JL; Grose, RP (2017-04-21)

A 3d In Vitro Model To Unravel Myoepithelial-Macrophage Interactions In Breast Cancer Progression

Roozitalab, R; Allen, M; Grose, RP (2022)

A 3D tumor microenvironment regulates cell proliferation, peritoneal growth and expression patterns.

Loessner, D; Rockstroh, A; Shokoohmand, A; Holzapfel, BM; Wagner, F; Baldwin, J; Boxberg, M; Schmalfeldt, B; Lengyel, E; Clements, JA (2019-01)

Peritoneal invasion through the mesothelial cell layer is a hallmark of ovarian cancer metastasis. Using tissue engineering technologies, we recreated an ovarian tumor microenvironment replicating this aspect of disease ...

450 CLONAL DYNAMICS AND CELL-OF-ORIGIN OF NORMAL HEPATOCYTE EXPANSIONS IN HOMEOSTATIC HUMAN LIVERS AND THEIR ASSOCIATION WITH THE BILIARY EPITHELIUM

Passman, AM; Haughey, MJ; Carlotti, E; Williams, M; Cereser, B; Russo, FP; Hoare, M; Kocher, H; Chin-Aleong, J; Graham, TA (Elsevier, 2020-05-01)

6: Development of non-invasive imaging of integrin alpha-v-beta-6 (αvβ6)-positive lung cancers in advance of testing αvβ6-targeted therapies

Rudran, B; Desai, A; Luzarraga, M; Hodivala-Dilke, K; Foster, J; Sosabowski, J; Marshall, J (Elsevier, 2017-01)

700PSTAR-PAC: Phase I clinical trial repurposing all trans retinoic acid (ATRA) as stromal targeting agent in a novel drug combination for pancreatic cancer

Kocher, HM; Basu, B; Froeling, FEM; Sarker, D; Slater, S; Carlin, D; Coetzee, C; de Souza, N; Goulart, M; Hughes, C (2019-10-01)

Abstract 4576: 3D in vitro models uncover malignant cell intrinsic and extrinsic mechanisms of CAR-T cell resistance in high grade serous ovarian cancer

Joy, JD; Malacrida, B; Laforêts, F; Kotantaki, P; Maniati, E; Hopkins, S; Garrobo-Calleja, I; Gautrot, J; Balkwill, F (American Association for Cancer Research (AACR), 2023-04-04)