• Prior antithrombotic therapy, particularly anticoagulant is associated with unfavorable outcomes in primary spontaneous intracerebral hemorrhage patients receiving craniotomy: A nationwide population-based cohort study. 

  Liu, Z-H; Chen, N-Y; Tu, P-H; Yip, PK; Wang, Y-C; Chen, C-C; Chuang, C-C; Liu, C-H; Hsu, P-W; Lin, Y-S (Elsevier, 2019-04-04)

  OBJECTIVE: The impact of antithrombotic agents on primary intracerebral hemorrhage (ICH) patients remains controversial, especially with patients that require emergent craniotomy. This study was to evaluate clinical outcomes ...

• Patient preferences for whole-body MRI or conventional staging pathways in lung and colorectal cancer: a discrete choice experiment 

  Miles, A; Taylor, SA; Evans, REC; Halligan, S; Beare, S; Bridgewater, J; Goh, V; Janes, S; Navani, N; Oliver, A (Springer Nature, 2019-04-01)

  Objectives: To determine the importance placed by patients on attributes associated with whole-body MRI (WB-MRI) and standard cancer staging pathways and ascertain drivers of preference. Methods: Patients recruited to ...

• Functional evaluation of transposable elements as enhancers in mouse embryonic and trophoblast stem cells. 

  Todd, CD; Deniz, Ö; Taylor, D; Branco, MR (eLife Sciences Publications, 2019-04-23)

  Transposable elements (TEs) are thought to have helped establish gene regulatory networks. Both the embryonic and extraembryonic lineages of the early mouse embryo have seemingly co-opted TEs as enhancers, but there is ...

• No evidence of disease activity in people with multiple sclerosis. 

  Marta, M (Wiley, 2018-08-13)

• The Hepatitis C Awareness Through to Treatment (HepCATT) study: improving the cascade of care for hepatitis C virus-infected people who inject drugs in England. 

  Harrison, GI; Murray, K; Gore, R; Lee, P; Sreedharan, A; Richardson, P; Hughes, AJ; Wiselka, M; Gelson, W; Unitt, E (2019-06)

  BACKGROUND AND AIMS: Previous studies have shown low rates of diagnosis and treatment of hepatitis C virus (HCV) infection in people who inject drugs (PWID). Our aims were to test the effect of a complex intervention ...

• Predicting seizures in pregnant women with epilepsy: Development and external validation of a prognostic model 

  ALLOTEY, JOHN; ZAMORA, J; KHAN, KS; THANGARATINAM, S; Fernandez-Felix, B M; Moss, N; Bagary, M; Kelso, A; Khan, R; van der Post, J (Public Library of Science (PLoS), 2019-05-13)

  Background: Seizures are the main cause of maternal death in women with epilepsy; but there are no tools for predicting seizures in pregnancy. We set out to develop and validate a prognostic model, using information ...

• FASN activity is important for the initial stages of the induction of senescence 

  Fafián-Labora, J; Carpintero-Fernández, P; Jordan, SJD; Shikh-Bahaei, T; Abdullah, SM; Mahenthiran, M; Rodríguez-Navarro, JA; Niklison-Chirou, MV; O’Loghlen, A (Springer Nature, 2019-04-08)

  Senescent cells accumulate in several tissues during ageing and contribute to several pathological processes such as ageing and cancer. Senescence induction is a complex process not well defined yet and is characterized ...

• What's new for trauma haemorrhage management? 

  Vulliamy, P; Thaventhiran, AJ; Davenport, RA (Mark Allen Healthcare, 2019-05-06)

  Uncontrolled haemorrhage is the leading cause of preventable death from injury and is a major contributor to the global burden of disease. The majority of deaths resulting from bleeding occur within the first 3 hours of ...

• Towards a standard MRI protocol for multiple sclerosis across the UK. 

  Schmierer, K; Campion, T; Sinclair, A; van Hecke, W; Matthews, PM; Wattjes, MP (British Institute of Radiology, 2019-04-17)

  Multiple sclerosis (MS) is a chronic inflammatory demyelinating and degenerative disease of the central nervous system. It is the most common non-traumatic cause of chronic disability in young adults. An early and accurate ...

• Economic shocks and health resilience: lessons from the Russian Federation (Corrigendum) 

  Gordeev, VS; Goryakin, Y; McKee, M; Stuckler, D; Roberts, B (Oxford University Press on behalf of Faculty of Public Health., 2017-07-13)

  This is a correction to: Journal of Public Health, Volume 38, Issue 4, December 2016, Pages e409–e418, https://doi.org/10.1093/pubmed/fdv166

• Economic shocks and health resilience: lessons from the Russian Federation 

  Gordeev, VS; Goryakin, Y; Mckee, M; Stuckler, D; Roberts, B (Oxford University Press (OUP), 2015-11-17)

  Background: Despite extensive research on determinants of health, there is much less information on factors protecting health among those exposed to economic shocks. Using longitudinal data from the Russian Federation in ...

• Diagnostic accuracy of whole-body MRI versus standard imaging pathways for metastatic disease in newly diagnosed colorectal cancer: the prospective Streamline C trial 

  Taylor, SA; Mallett, S; Beare, S; Bhatnagar, G; Blunt, D; Boavida, P; Bridgewater, J; Clarke, CS; Duggan, M; Ellis, S (Elsevier, 2019-03-09)

  Background: Whole-body MRI (WB-MRI) could be an alternative to multimodality staging of colorectal cancer, but its diagnostic accuracy, effect on staging times, number of tests needed, cost, and effect on treatment decisions ...

• Blood transcriptomic stratification of short-term risk in contacts of tuberculosis. 

  Roe, J; Venturini, C; Gupta, RK; Gurry, C; Chain, BM; Sun, Y; Southern, J; Jackson, C; Lipman, MC; Miller, RF (2019-03-28)

  BACKGROUND: The highest risk of tuberculosis (TB) arises in the first few months after exposure. We reasoned that this risk reflects incipient disease among TB contacts. Blood transcriptional biomarkers of TB may predate ...

• "Every Newborn-BIRTH" protocol: observational study validating indicators for coverage and quality of maternal and newborn health care in Bangladesh, Nepal and Tanzania. 

  Day, LT; Ruysen, H; Gordeev, VS; Gore-Langton, GR; Boggs, D; Cousens, S; Moxon, SG; Blencowe, H; Baschieri, A; Rahman, AE (Edinburgh University Global Health Society, 2019-06)

  Background: To achieve Sustainable Development Goals and Universal Health Coverage, programmatic data are essential. The Every Newborn Action Plan, agreed by all United Nations member states and >80 development partners, ...

• Human Semaphorin 3 Variants Link Melanocortin Circuit Development and Energy Balance. 

  van der Klaauw, AA; Croizier, S; Mendes de Oliveira, E; Stadler, LKJ; Park, S; Kong, Y; Banton, MC; Tandon, P; Hendricks, AE; Keogh, JM (Elsevier Inc., 2019-01-17)

  Hypothalamic melanocortin neurons play a pivotal role in weight regulation. Here, we examined the contribution of Semaphorin 3 (SEMA3) signaling to the development of these circuits. In genetic studies, we found 40 rare ...

• Physical activity among children with asthma: Cross-sectional analysis in the UK millennium cohort. 

  Pike, KC; Griffiths, LJ; Dezateux, C; Pearce, A (Wiley, 2019-03-18)

  BACKGROUND: Although beneficial for health and well-being, most children do not achieve recommended levels of physical activity. Evidence for children with asthma is mixed, with symptom severity rarely considered. This ...

• Prescribed analgesics in pregnancy and risk of childhood asthma. 

  Shaheen, SO; Lundholm, C; Brew, BK; Almqvist, C (2019-03-17)

  Many epidemiological studies have reported a positive association between prenatal exposure to paracetamol and childhood wheezing and asthma. We investigated whether the link between prenatal analgesic exposure and ...

• Lipids in the intensive care unit: Recommendations from the ESPEN Expert Group. 

  Calder, PC; Adolph, M; Deutz, NE; Grau, T; Innes, JK; Klek, S; Lev, S; Mayer, K; Michael-Titus, AT; Pradelli, L (2018-02)

  This article summarizes the presentations given at an ESPEN Workshop on "Lipids in the ICU" held in Tel Aviv, Israel in November 2014 and subsequent discussions and updates. Lipids are an important component of enteral and ...

• Aspirin blocks formation of metastatic intravascular niches by inhibiting platelet-derived COX-1/thromboxane A2. 

  Lucotti, S; Cerutti, C; Soyer, M; Gil-Bernabé, AM; Gomes, AL; Allen, PD; Smart, S; Markelc, B; Watson, K; Armstrong, PC (2019-03-25)

  Because metastasis is associated with the majority of cancer-related deaths, its prevention is a clinical aspiration. Prostanoids are a large family of bioactive lipids derived from the activity of cyclooxygenase-1 (COX-1) ...

• Reply. 

  Kennedy, P; Bertoletti, A; Mason, W (Elsevier, 2017-03-06)

  Reply. Refers to: Yun-Fan Liaw, Chia-Ming Chu Immune Tolerance Phase of Chronic Hepatitis B Gastroenterology, Volume 152, Issue 5, April 2017, Pages 1245-1246

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