Centre for Immunobiology
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The Centre for Immunobiology combines top-quality research and education in immunology, with particular focus on acute and chronic inflammatory disease, lymphocyte development, and the mucosal immune system.
Recent Submissions
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Differential immunogenicity of homologous versus heterologous boost in Ad26.COV2.S vaccine recipients.
(2022-02-11)Background: Protection offered by coronavirus disease 2019 (COVID-19) vaccines wanes over time, requiring an evaluation of different boosting strategies to revert such a trend and enhance the quantity and quality of ... -
A feasibility study evaluating the uptake, effectiveness and acceptability of routine screening of pregnant migrants for latent tuberculosis infection in antenatal care: a research protocol.
(2022-04-04)INTRODUCTION: Globally, tuberculosis (TB) is a leading cause of death in women of reproductive age and there is high risk of reactivation of latent tuberculosis infection (LTBI) in pregnancy. The uptake of routine screening ... -
Epithelial Abnormalities in the Small Intestine of Zambian Children With Stunting.
(2022)Background: Environmental enteropathy (EE) contributes to impaired linear growth (stunting), in millions of children worldwide. We have previously reported that confocal laser endomicroscopy (CLE) shows fluorescein leaking ... -
Ethnic disparities in hospitalisation and hospital-outcomes during the second wave of COVID-19 infection in east London.
(2022-03-08)It is unclear if changes in public behaviours, developments in COVID-19 treatments, improved patient care, and directed policy initiatives have altered outcomes for minority ethnic groups in the second pandemic wave. This ... -
Pulmonary tuberculosis in intensive care setting, with a focus on the use of severity scores, a multinational collaborative systematic review.
(2022-02-26)BACKGROUND AND AIM: Tuberculosis (TB) is associated with a high mortality in the intensive care unit (ICU), especially in subjects with Acute Respiratory Distress Syndrome (ARDS) requiring mechanical ventilation. Despite ... -
Advantages of Proactive Therapeutic Drug Monitoring in a Prospective Cohort of Children With Inflammatory Bowel Disease Treated With Anti-TNF.
(2022-02-03)ABSTRACT: Few studies have addressed whether proactive therapeutic drug monitoring (TDM) results in improved clinical outcomes in children with inflammatory bowel disease (IBD) treated with anti-TNF. The aim of this study ...