Centre for Genomics and Child Health
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The Centre for Genomics and Child Health brings together clinical and non-clinical scientists researching genomics in order to address the biology of health and human disease. This research has strong translational links to many clinical diseases, particularly those prevalent in childhood.
Recent Submissions
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Air pollution and respiratory inequality: Lessons from high-income countries
(2023-01-01)Within urban areas in HICs, zones of increased air pollution occur along heavily used roads. As high-pollution zones are more likely to be located in the most-deprived neighbourhoods, and people living in these neighbourhoods ... -
Defining the in vivo mechanism of air pollutant toxicity using murine stress response biomarkers.
(2023-05-15)Air pollution can cause a wide range of serious human diseases. For the informed instigation of interventions which prevent these outcomes there is an urgent need to develop robust in vivo biomarkers which provide insights ... -
Rare variant contribution to cholestatic liver disease in a South Asian population in the United Kingdom.
(2023-05-19)This study assessed the contribution of five genes previously known to be involved in cholestatic liver disease in British Bangladeshi and Pakistani people. Five genes (ABCB4, ABCB11, ATP8B1, NR1H4, TJP2) were interrogated ... -
The Clinical Picture of the ERCC6L2 Disease - from Bone Marrow Failure to Acute Leukemia.
(2023-03-23)Biallelic germline ERCC6L2 variants strongly predispose to bone marrow failure (BMF) and myeloid malignancies characterized by somatic TP53-mutated clones and erythroid predominance. We present a series of 52 subjects (35 ... -
Revision of RUNX1 variant curation rules.
(2022-08-23) -
Effects of oral probiotic supplements on vaginal microbiota during pregnancy: a randomised, double-blind, placebo-controlled trial with microbiome analysis
(Blackwell Publishing Inc., 2019-04-01) -
Glucose testing in the neonate
(Elsevier, 1997-05-29) -
Magnesium and pregnancy
(S. Karger AG, 2023-01-01)