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Increased Dose of Inhaled Corticosteroid versus Add-On Long-acting β-Agonist for Step-Up Therapy in Asthma.
(2015-06)
RATIONALE: Guidelines advocate adding long-acting β-agonist (LABA) to inhaled corticosteroid as the preferred step-up therapy to increasing inhaled corticosteroid dose for patients with uncontrolled asthma on inhaled ...
Maternal 25-hydroxyvitamin D and its association with childhood atopic outcomes and lung function.
(2013-10)
BACKGROUND: It has been suggested that maternal vitamin D status in pregnancy influences the risk of asthma and atopy in the offspring. The epidemiological evidence to support these claims is conflicting and may reflect ...
Twenty-eight day safety, antiviral activity, and pharmacokinetics of tenofovir alafenamide for treatment of chronic hepatitis B infection.
(2015-03)
BACKGROUND & AIMS: Tenofovir alafenamide, a phosphonate prodrug of tenofovir with greater plasma stability than tenofovir disoproxil fumarate, provides efficient delivery of active drug to hepatocytes at reduced systemic ...
Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion
(2013)
Prevalence of colorectal cancer (CRC) in the British Bangladeshi population (BAN) is low compared to British Caucasians (CAU). Genetic background may influence mutations and disease features.
Predictive value of S100-B and copeptin for outcomes following seizure: the BISTRO International Cohort Study.
(2015)
OBJECTIVE: To evaluate the performance of S100-B protein and copeptin, in addition to clinical variables, in predicting outcomes of patients attending the emergency department (ED) following a seizure. METHODS: We prospectively ...
[Psychiatric disorders in emigrants. III. Follow-up after two and a half years].
(1993-01)
In the first and the second part of this study we reported about first examination and a six month follow-up in patients who had left East-Germany in 1989. In this third and last part, findings of a two and a half year ...
Gastric output of pancreatic secretory trypsin inhibitor is increased by misoprostol.
(1991-11)
Pancreatic secretory trypsin inhibitor (PSTI) is a potent protease inhibitor that also has growth promoting activity. It has recently been identified in the foveolar cells of the stomach, which secrete mucus. We examined ...
Suppression of Helicobacter pylori reduces gastrin releasing peptide stimulated gastrin release in duodenal ulcer patients.
(1992-05)
Helicobacter pylori increases gastrin release in duodenal ulcer patients. This may be through disruption or changes in the mucus layer affecting the access of luminal stimulants to gastrin releasing cells. The effect of ...
Pancreatic secretory trypsin inhibitor in gastrointestinal mucosa and gastric juice.
(1990-11)
We studied the distribution of pancreatic secretory trypsin inhibitor (PSTI) in the epithelia of the gastrointestinal tract and determined whether PSTI is secreted into gastric juice. PSTI was measured by a specific ...
[Psychiatric disorders in emigrants. II. Follow-up over six months and attitudes of the patients].
(1993-01)
In the first part of this study we investigated people who had left East Germany and sought psychiatric help within six weeks after their move. 94 patients were re-examined approximately six month later. Meanwhile 40% had ...