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Deep Sequencing of B Cell Receptor Repertoires From COVID-19 Patients Reveals Strong Convergent Immune Signatures.
(2020)
Deep sequencing of B cell receptor (BCR) heavy chains from a cohort of 31 COVID-19 patients from the UK reveals a stereotypical naive immune response to SARS-CoV-2 which is consistent across patients. Clonal expansion of ...
Gender disparities in COVID-19 clinical trial leadership.
(2021-01-05)
OBJECTIVES: We aimed to compare the gender distribution of clinical trial leadership in COVID-19 clinical trials. METHODS: We searched https://clinicaltrials.gov/and retrieved all clinical trials on COVID-19 from January ...
Genomewide Association Study of Severe Covid-19 with Respiratory Failure.
(2020-10-15)
BACKGROUND: There is considerable variation in disease behavior among patients infected with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (Covid-19). Genomewide ...
REducing unwarranted variation in the Delivery of high qUality hip fraCture services in England and Wales (REDUCE): protocol for a mixed-methods study.
(2021-05-19)
INTRODUCTION: Substantial variation in the delivery of hip fracture care, and patient outcomes persists between hospitals, despite established UK national standards and guidelines. Patients' outcomes are partly explained ...
Outcomes from elective colorectal cancer surgery during the SARS-CoV-2 pandemic
(Wiley, 2021-11-15)
A retrospective cohort study of risk factors and outcomes in older patients admitted to an inner-city geriatric unit in London during first peak of COVID-19 pandemic.
(2021-07-06)
PURPOSE: Compared to younger patients, coronavirus disease 2019 (COVID-19) clinical presentation in older people can be more heterogeneous and fatal. We aim to describe a cohort of older adults admitted in an inner-city ...
Childhood asthma outcomes during the COVID-19 pandemic: Findings from the PeARL multi-national cohort.
(2021-06)
BACKGROUND: The interplay between COVID-19 pandemic and asthma in children is still unclear. We evaluated the impact of COVID-19 pandemic on childhood asthma outcomes. METHODS: The PeARL multinational cohort included 1,054 ...
