Centre for Neuroscience, Surgery and Trauma
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Neuroscience, Surgery and Trauma research at Barts and The London covers a wide range of topics: general trauma and neurotrauma, neurodegeneration, neuroimmunology, NBRC and Neurogastroenterology.
Recent Submissions
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GPR84 in physiology-Many functions in many tissues.
(2023-08-02)Members of the GPCR superfamily have a wide variety of physiological roles and are therefore valuable targets for developing effective medicines. However, within this superfamily are receptors that are less well characterized ... -
Habit training versus habit training with direct visual biofeedback in adults with chronic constipation: A randomized controlled trial.
(2023-09-08)AIM: The aim was to determine whether specialist-led habit training using Habit Training with Biofeedback (HTBF) is more effective than specialist-led habit training alone (HT) for chronic constipation and whether outcomes ... -
Gastrointestinal Transit Times in Health as Determined Using Ingestible Capsule Systems: A Systematic Review.
(2023-08-13)BACKGROUND: Ingestible capsule (IC) systems can assess gastrointestinal (GI) transit times as a surrogate for gut motility for extended periods of time within a minimally invasive, radiation-free and ambulatory setting. ... -
Patient-reported outcomes in multiple sclerosis: a prospective registry cohort study.
(2023)Registries have the potential to tackle some of the current limitations in determining the long-term impact of multiple sclerosis. Online assessments using patient-reported outcomes can streamline follow-up enabling ... -
Surgical experience and identification of errors in laparoscopic cholecystectomy.
(2023-08-23)BACKGROUND: Surgical errors are acts or omissions resulting in negative consequences and/or increased operating time. This study describes surgeon-reported errors in laparoscopic cholecystectomy. METHODS: Intraoperative ... -
Defining core patient descriptors for perforated peptic ulcer research: international Delphi.
(2022-06-14)BACKGROUND: Perforated peptic ulcer (PPU) remains a common condition globally with significant morbidity and mortality. Previous work has demonstrated variation in reporting of patient characteristics in PPU studies, making ... -
The Clinical Impact of Obesity in Patients With Disorders of Defecation: A Cross-Sectional Study of 1,155 Patients.
(2023-08-18)INTRODUCTION: Obesity is a global epidemic. Its clinical impact on symptoms of fecal incontinence (FI) and/or constipation and underlying anorectal pathophysiology remains uncertain. METHODS: This is a cross-sectional study ...