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Enhancing nuclear translocation: perspectives in inhaled corticosteroid therapy

Hakim, A; Usmani, OS (Future Science Ltd, 2015-05-21)

Corticosteroids are widely used in the treatment of asthma and chronic obstructive pulmonary disease (COPD). In contrast to their use in mild-to-moderate asthma, they are less efficacious in improving lung function and ...
Restoration of Corticosteroid Sensitivity by p38 Mitogen Activated Protein Kinase Inhibition in Peripheral Blood Mononuclear Cells from Severe Asthma

Mercado, N; Hakim, A; Kobayashi, Y; Meah, S; Usmani, OS; Chung, KF; Barnes, PJ; Ito, K (Public Library of Science, 2012-07-23)

Background Severe asthma accounts for a small number of asthmatics but represents a disproportionate cost to health care systems. The underlying mechanism in severe asthma remains unknown but several mechanisms are likely ...

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