Browsing Centre for Cell Biology and Cutaneous Research by Title
Now showing items 316-335 of 380
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Signalling Properties of Inositol Polyphosphates
(MDPI, 2020-11-12)Several studies have identified specific signalling functions for inositol polyphosphates (IPs) in different cell types and have led to the accumulation of new information regarding their cellular roles as well as new ... -
Sonic Hedgehog signaling limits atopic dermatitis via Gli2-driven immune regulation.
(2019-07-02)Hedgehog (Hh) proteins regulate development and tissue homeostasis, but their role in atopic dermatitis (AD) remains unknown. We found that on induction of mouse AD, Sonic Hedgehog (Shh) expression in skin, and Hh pathway ... -
Stem cell therapy for stress urinary incontinence: a systematic review in human subjects.
(2013-12)PURPOSE: To systematically evaluate the current evidence on the safety and efficacy of stem cell therapy (SCT) in stress urinary incontinence (SUI) to allow objective comparison with existing surgical techniques. METHODS: ... -
Structural basis for the modulation of MRP2 activity by phosphorylation and drugs.
(2024-03-04)Multidrug resistance-associated protein 2 (MRP2/ABCC2) is a polyspecific efflux transporter of organic anions expressed in hepatocyte canalicular membranes. MRP2 dysfunction, in Dubin-Johnson syndrome or by off-target ...