Browsing Centre for Cell Biology and Cutaneous Research by Title

Kallikrein-Mediated Cytokeratin 10 Degradation Is Required for Varicella Zoster Virus Propagation in Skin.

Tommasi, C; Rogerson, C; Depledge, DP; Jones, M; Naeem, AS; Venturini, C; Frampton, D; Tutill, HJ; Way, B; Breuer, J (2020-04)

Varicella zoster virus (VZV) is a skin-tropic virus that infects epidermal keratinocytes and causes chickenpox. Although common, VZV infection can be life-threatening, particularly in the immunocompromized. Therefore, ...

Key differences identified between actinic keratosis and cutaneous squamous cell carcinoma by transcriptome profiling

Lambert, SR; Mladkova, N; Gulati, A; Hamoudi, R; Purdie, K; Cerio, R; Leigh, I; Proby, C; Harwood, CA (2014-01-21)

Killer Cell Lectin-like Receptor G1 Inhibits NK Cell Function through Activation of Adenosine 5 '-Monophosphate-Activated Protein Kinase

Mueller-Durovic, B; Lanna, A; Covre, LP; Mills, RS; Henson, SM; Akbar, AN (2016-10-01)

Laminin 332: bottom-up control of the skin barrier?

Jones, EM; Marsh, ST; O'Shaughnessy, RF; Aumailley, M; Camera, E; Picardo, M; McGrath, JA; O'Toole, EA; Caley, MP (2019-06)

Landscaper seeks remunerative position

Playford, RJ (2001-05)

Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array

Rodriguez, S; Gaunt, TR; Guo, Y; Zheng, J; Barnes, MR; Tang, W; Danish, F; Johnson, A; Castillo, BA; Li, YR (2016-01)

London calling Gaza: The role of international collaborations in the globalisation of postgraduate burn care education.

Theodorakopoulou, E; Goutos, I; Mason, K; Ghanem, AM; Myers, S (2019)

Burn injuries represent a significant epidemiological problem, with the vast majority occurring in low- to middle-income countries. These regions also represent areas where lack of socioeconomic growth and geopolitical ...

Long-Term Safety and Efficacy of Recombinant Factor VIII FC (RFVIIIFC) in Adults and Adolescents With Severe Haemophilia A: An Interim Analysis of The ASPIRE Study

Pasi, J; Perry, D; Mahlangu, J; Konkle, B; Rangarajan, S; Brown, SA; Hanabusa, H; Jackson, S; Pabinger-Fasching, I; Cristiano, LM (2015-01)

Loss of Laminin alpha 3 drives SCC invasion via ROCK signalling

Caley, M; Martins, V; Moore, K; Lashari, M; Kahari, V; Nissinen, L; Donaldson, M; Marshall, J; O'Toole, EA (2016-09)

Loss of Laminin α3 induces cell invasion and macrophage infiltration in cutaneous squamous cell carcinoma.

Caley, MP; Martins, VL; Moore, K; Lashari, M; Nissinen, L; Kähäri, V-M; Alexander, S; Jones, E; Harwood, CA; Jones, J (2020-08-07)

BACKGROUND: Cutaneous squamous cell carcinoma (cSCC) is a common cancer which invades into dermis through the basement membrane. The role of the basement membrane in poorly differentiated cSCC is poorly understood. OBJECTIVES: ...

Loss-of-function desmoplakin I and II mutations underlie dominant arrhythmogenic cardiomyopathy with a hair and skin phenotype.

Maruthappu, T; Posafalvi, A; Castelletti, S; Delaney, PJ; Syrris, P; O'Toole, EA; Green, KJ; Elliott, PM; Lambiase, PD; Tinker, A (2018-01-02)

BACKGROUND: Arrhythmogenic cardiomyopathy (AC) is an inherited, frequently underdiagnosed disorder, which can predispose individuals to sudden cardiac death. Rare, recessive forms of AC can be associated with woolly hair ...

Loss-of-Function Mutations in CAST Cause Peeling Skin, Leukonychia, Acral Punctate Keratoses, Cheilitis, and Knuckle Pads

Lin, Z; Zhao, J; Nitoiu, D; Scott, CA; Plagnol, V; Smith, FJD; Wilson, NJ; Cole, C; Schwartz, ME; McLean, WHI (2015-03-05)

Loss-of-Function Mutations in SERPINB8 Linked to Exfoliative Ichthyosis with Impaired Mechanical Stability of Intercellular Adhesions

Pigors, M; Sarig, O; Heinz, L; Plagnol, V; Fischer, J; Mohamad, J; Malchin, N; Rajpopat, S; Kharfi, M; Lestringant, GG (2016-08-04)

Low Serum Levels of MicroRNA-19 Are Associated with a Stricturing Crohn's Disease Phenotype

Lewis, A; Mehta, S; Hanna, LN; Rogalski, LA; Jeffery, R; Nijhuis, A; Kumagai, T; Biancheri, P; Bundy, JG; Bishop, CL (2015-08)

Maternal VDR variants rather than 25-hydroxyvitamin D concentration during early pregnancy are associated with type 1 diabetes in the offspring

Miettinen, ME; Smart, MC; Kinnunen, L; Mathews, C; Harjutsalo, V; Surcel, H-M; Lamberg-Allardt, C; Tuomilehto, J; Hitman, GA (2015-10)

MCL-1 is modulated in Crohn's disease fibrosis by miR-29b via IL-6 and IL-8

Nijhuis, A; Curciarello, R; Mehta, S; Feakins, R; Bishop, CL; Lindsay, JO; Silver, A (2017-05)

A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a novel mechanism for skin barrier disruption in patients with atopic dermatitis.

Naeem, AS; Tommasi, C; Cole, C; Brown, SJ; Zhu, Y; Way, B; Willis Owen, SAG; Moffatt, M; Cookson, WO; Harper, JI (2017-04)

BACKGROUND: Filaggrin, which is encoded by the filaggrin gene (FLG), is an important component of the skin's barrier to the external environment, and genetic defects in FLG strongly associate with atopic dermatitis (AD). ...