Browsing Centre for Cell Biology and Cutaneous Research by Title
Now showing items 250-269 of 364
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O13 JAK inhibitors to restore skin barrier function in ARCI
(Oxford University Press (OUP), 2023-07-07) -
Orchestrated control of filaggrin-actin scaffolds underpins cornification.
(2018-04-01)Epidermal stratification critically depends on keratinocyte differentiation and programmed death by cornification, leading to formation of a protective skin barrier. Cornification is dynamically controlled by the protein ... -
P2X7 in Cancer: From Molecular Mechanisms to Therapeutics
(2020-06-04) -
Percutaneous collagen induction (microneedling) for the management of non-atrophic scars: literature review.
(2019-01)Introduction: Percutaneous collagen induction (PCI) or needling techniques are increasingly popular in the reconstructive and aesthetic arena. The underlying mechanisms of action rest on producing a pattern of non-ablative ... -
Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity.
(2017-11)BACKGROUND: Upregulation of kallikreins (KLKs) including KLK5 has been reported in atopic dermatitis (AD). KLK5 has biological functions that include degrading desmosomal proteins and inducing proinflammatory cytokine ...