• Abstract LB195: Immunotherapies that repolarize macrophages and CD4 T cells enhance the effect of chemotherapy in high-grade serous ovarian cancer 

  Elorbany, S; Berlato, C; Carnevalli, L; Maniati, E; Wang, J; Barry, S; Manchanda, R; Kzhyshkowska, J; Balkwill, F (2023-04-14)

• Systematic Review and Narrative Synthesis of Economic Evaluations of Prostate Cancer Diagnostic Pathways Incorporating Prebiopsy Magnetic Resonance Imaging. 

  Merriel, SWD; Hall, R; Walter, FM; Hamilton, W; Spencer, AE (2023-06)

  CONTEXT: Prebiopsy magnetic resonance imaging (MRI) of the prostate has been shown to increase the accuracy of the diagnosis of clinically significant prostate cancer. However, evidence is still evolving about how best to ...

• Improving the diagnostic process for patients with possible bladder and kidney cancer: a mixed-methods study to identify potential missed diagnostic opportunities. 

  Zhou, Y; Singh, H; Hamilton, W; Archer, S; Tan, S; Brimicombe, J; Lyratzopoulos, G; Walter, FM (2023-03-30)

  BACKGROUND: Patients with bladder and kidney cancer may experience diagnostic delays. AIM: To identify patterns of suboptimal care and contributors of potential missed diagnostic opportunities (MDOs). DESIGN AND SETTING: ...

• Should we? Could we? Feasibility of interventions to support prevention or early diagnosis of future cancer following urgent referral: A qualitative study. 

  Evans, REC; Waller, J; Nicholson, BD; Round, T; Gildea, C; Smith, D; Scott, SE (2023-07)

  OBJECTIVE: This study investigated perspectives of healthcare professionals (HCPs) on the feasibility of giving additional support to patients after cancer is not found following urgent referral. We sought to understand ...

• Renal transplant and haemostasis: early post-operative changes in recipients and donors 

  Kohli, R; Platton, S; Forbes, S; Thuraisingham, R; Tan, J; Green, L; MacCallum, P (2023-04-01)

• A proteomic survival predictor for COVID-19 patients in intensive care. 

  Demichev, V; Tober-Lau, P; Nazarenko, T; Lemke, O; Kaur Aulakh, S; Whitwell, HJ; Röhl, A; Freiwald, A; Mittermaier, M; Szyrwiel, L (2022-01)

  Global healthcare systems are challenged by the COVID-19 pandemic. There is a need to optimize allocation of treatment and resources in intensive care, as clinically established risk assessments such as SOFA and APACHE II ...

• Immunoglobulin, glucocorticoid, or combination therapy for multisystem inflammatory syndrome in children: a propensity-weighted cohort study. 

  Channon-Wells, S; Vito, O; McArdle, AJ; Seaby, EG; Patel, H; Shah, P; Pazukhina, E; Wilson, C; Broderick, C; D'Souza, G (2023-04)

  BACKGROUND: Multisystem inflammatory syndrome in children (MIS-C), a hyperinflammatory condition associated with SARS-CoV-2 infection, has emerged as a serious illness in children worldwide. Immunoglobulin or glucocorticoids, ...

• Urine biomarkers enable pancreatic cancer detection up to 2 years before diagnosis 

  Debernardi, S; Blyuss, O; Rycyk, D; Srivastava, K; Jeon, CY; Cai, H; Cai, Q; Shu, X-O; Crnogorac-Jurcevic, T (2023-02-15)

• Defining the road map to a UK national lung cancer screening programme. 

  O'Dowd, EL; Lee, RW; Akram, AR; Bartlett, EC; Bradley, SH; Brain, K; Callister, MEJ; Chen, Y; Devaraj, A; Eccles, SR (2023-05)

  Lung cancer screening with low-dose CT was recommended by the UK National Screening Committee (UKNSC) in September, 2022, on the basis of data from trials showing a reduction in lung cancer mortality. These trials provide ...

• Age-specific effects of childhood body mass index on multiple sclerosis risk 

  Hone, L; Jacobs, BM; Marshall, C; Giovannoni, G; Noyce, A; Dobson, R (2022-05-09)

• No evidence for an association between alcohol consumption and Multiple Sclerosis risk: a UK Biobank study 

  Dreyer-Alster, S; Achiron, A; Giovannoni, G; Jacobs, BMM; Dobson, R (2022-12-22)

• Exploring the barriers and facilitators of implementing CanRisk in primary care: a qualitative thematic framework analysis 

  Archer, S; Donoso, FS; Carver, T; Yue, A; Cunningham, AP; Ficorella, L; Tischkowitz, M; Easton, DF; Antoniou, AC; Emery, J (2023-04-12)

• Symptoms and signs of lung cancer prior to diagnosis: case-control study using electronic health records from ambulatory care within a large US-based tertiary care centre. 

  Prado, MG; Kessler, LG; Au, MA; Burkhardt, HA; Zigman Suchsland, M; Kowalski, L; Stephens, KA; Yetisgen, M; Walter, FM; Neal, RD (2023-04-20)

  OBJECTIVE: Lung cancer is the most common cause of cancer-related death in the USA. While most patients are diagnosed following symptomatic presentation, no studies have compared symptoms and physical examination signs at ...

• The Scare 2023 guideline: Updating consensus surgical case report (SCARE) guidelines. 

  Sohrabi, C; Mathew, G; Maria, N; Kerwan, A; Franchi, T; Agha, RA; Collaborators (2023-04-05)

  BACKGROUND: The Surgical CAse REport (SCARE) guidelines were first published in 2016 as a tool for surgeons to document and report their surgical cases in a standardised and comprehensive manner. However, with advances in ...

• Effectiveness of group arts therapies (art therapy, dance movement therapy and music therapy) compared to group counselling for diagnostically heterogeneous psychiatric community patients: Study protocol for a randomised controlled trial in mental health services (the ERA study). 

  Carr, C; medlicott, E; Hooper, R; Feng, Y; Mihaylova, B; Priebe, S

• Hepatocytes undergo punctuated expansion dynamics from a periportal stem cell niche in normal human liver. 

  Passman, AM; Haughey, MJ; Carlotti, E; Williams, MJ; Cereser, B; Lin, ML; Devkumar, S; Gabriel, JP; Gringeri, E; Cillo, U (2023-04-21)

  BACKGROUND: Normal human liver is thought to be generally quiescent, however clonal hepatocyte expansions have been observed but neither their cellular source nor their expansion dynamics have been determined. Knowing the ...

• Changing from face-to-face to virtual meetings due to the COVID-19 pandemic: protocol for a mixed-methods study exploring the impact on cancer multidisciplinary team (MDT) meetings. 

  McInnerney, D; Chung, D; Mughal, M; Onifade, A; Holden, D; Goodman, J; Birchall, M; Peake, MD; Quaife, SL (2023-04-19)

  INTRODUCTION: In the UK, the National Cancer Plan (2000) requires every cancer patient's care to be reviewed by a multidisciplinary team (MDT). Since the introduction of these guidelines, MDTs have faced escalating demands ...

• Homologous recombination deficiency in newly diagnosed FIGO stage III/IV high-grade epithelial ovarian cancer: a multi-national observational study. 

  Morgan, RD; Clamp, AR; Barnes, BM; Timms, K; Schlecht, H; Yarram-Smith, L; Wallis, Y; Valganon-Petrizan, M; MacMahon, S; White, R (2023-04-24)

  OBJECTIVE: Olaparib plus bevacizumab maintenance therapy improves survival outcomes in women with newly diagnosed, advanced, high-grade ovarian cancer with a deficiency in homologous recombination. We report data from the ...

• Anthracycline-containing and taxane-containing chemotherapy for early-stage operable breast cancer: a patient-level meta-analysis of 100 000 women from 86 randomised trials. 

  Early Breast Cancer Trialists’ Collaborative Group (EBCTCG). Electronic address: bc.overview@ctsu.ox.ac.uk (2023-04-15)

  BACKGROUND: Anthracycline-taxane chemotherapy for early-stage breast cancer substantially improves survival compared with no chemotherapy. However, concerns about short-term and long-term side-effects of anthracyclines ...

• Cell Competition in Carcinogenesis 

  Madan, E; Palma, AM; Vudatha, V; Trevino, JG; Natarajan, KN; Winn, RA; Won, KJ; Graham, TA; Drapkin, R; McDonald, SAC (2022-12-15)

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