RSS 1.0Centre for Psychiatry
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Ethnic inequalities and pathways to care in psychosis in England: a systematic review and meta-analysis.
(2018-12-12)BACKGROUND: As part of a national programme to tackle ethnic inequalities, we conducted a systematic review and meta-analysis of research on ethnic inequalities in pathways to care for adults with psychosis living in England ... -
Ethnic variations in detention under the Mental Health Act: a Systematic Review and Meta-Analysis
Background: Evidence suggests Black, Asian and Minority Ethnic (BAME) groups are at increased risk of involuntary psychiatric care. However, there is no published meta-analysis which brings together both international ... -
Evaluating the effects of community treatment orders (CTOs) in England using the Mental Health Services Dataset (MHSDS): protocol for a national, population-based study.
(2018-10-18)INTRODUCTION: Supervised community treatment (SCT) for people with serious mental disorders has become accepted practice in many countries around the world. In England, SCT was adopted in 2008 in the form of community ... -
Characteristics, motivations and experiences of volunteer befrienders for people with mental illness
(BioMed Central, 2018-12-04)Background The literature suggests that many people in the general population tend to distance themselves from those with mental illness. However, there are volunteers that behave differently, spending their free time ... -
Predictors of personal continuity of care of patients with severe mental illness: A comparison across five European countries.
(2018-12-21)BACKGROUND: In Europe, at discharge from a psychiatric hospital, patients with severe mental illness may be exposed to one of two main care approaches: personal continuity, where one clinician is responsible for in- and ... -
The same or different psychiatrists for in- and out-patient treatment? A multi-country natural experiment.
(2018-12-18)AimsA core question in the debate about how to organise mental healthcare is whether in- and out-patient treatment should be provided by the same (personal continuity) or different psychiatrists (specialisation). The ... -
Ethnic variation in personality disorder: Evaluation of 6 years of hospital admissions
(2018-08-01)© The Authors 2018 Aims and method: There is limited evidence on ethnic differences in personality disorder prevalence rates. We compared rates of people with personality disorder admitted to hospital in East London from ... -
What drives changes in institutionalised mental health care? A qualitative study of the perspectives of professional experts.
(2018-11-23)BACKGROUND: Since 1990, the provision of mental healthcare has changed substantially across Western Europe. There are fewer psychiatric hospital beds and more places in forensic psychiatric hospitals and residential ... -
Staff and patient perspectives on therapeutic engagement during one-to-one observation.
(2018-11)WHAT IS KNOWN ON THE SUBJECT?: One-to-one observation uses continuous staff observation to safeguard patients judged likely to harm themselves or others. Policies increasingly mandate that staff engage therapeutically with ... -
Childhood maltreatment and adult medical morbidity in mood disorders: comparison of unipolar depression with bipolar disorder.
(2018-11)BACKGROUND: The medical burden in mood disorders is high; various factors are thought to drive this pattern. Little research has examined the role of childhood maltreatment and its effects on medical morbidity in adulthood ... -
A weighted burden test using logistic regression for integrated analysis of sequence variants, copy number variants and polygenic risk score.
(2019-01)Previously described methods of analysis allow variants in a gene to be weighted more highly according to rarity and/or predicted function and then for the variant contributions to be summed into a gene-wise risk score, ... -
Attitudes towards severe mental illness and social distance: A survey of volunteer befrienders in Austria.
(2018-08)BACKGROUND: Research suggests there is a propensity for people in the general population to distance themselves from people with severe mental illness (SMI), which reportedly decreases with increased contact with individuals ... -
Ashes to Ashes.
(2018-01) -
Interviews following physical trauma: A thematic analysis.
(2018-09-24)INTRODUCTION: Mental health problems are common in trauma survivors. In particular, depression, anxiety, acute stress disorder and post-traumatic stress disorder. Yet little is known about how these can be brought to the ... -
Genetic correlation between amyotrophic lateral sclerosis and schizophrenia.
(2017-03-21)We have previously shown higher-than-expected rates of schizophrenia in relatives of patients with amyotrophic lateral sclerosis (ALS), suggesting an aetiological relationship between the diseases. Here, we investigate the ... -
Exome sequence analysis and follow up genotyping implicates rare ULK1 variants to be involved in susceptibility to schizophrenia
(2018-03-05)© 2017 John Wiley & Sons Ltd/University College London. Schizophrenia (SCZ) is a severe, highly heritable psychiatric disorder. Elucidation of the genetic architecture of the disorder will facilitate greater understanding ... -
Polygenic risk score for schizophrenia is not strongly associated with the expression of specific genes or gene sets.
(2018-08)BACKGROUND: The polygenic risk score (PRS) is derived from single nucleotide polymorphisms (SNPs) including those that are genome-wide significant and also including a large number of others more weakly associated with ...
