Recent Submissions

  • Tumor copy number alteration burden is a pan-cancer prognostic factor associated with recurrence and death. 

    Hieronymus, H; Murali, R; Tin, A; Yadav, K; Abida, W; Moller, H; Berney, D; Scher, H; Carver, B; Scardino, P;... (eLife, 2018-09-04)
    The level of copy number alteration (CNA), termed CNA burden, in the tumor genome is associated with recurrence of primary prostate cancer. Whether CNA burden is associated with prostate cancer survival or outcomes in other ...
  • Methylation of HPV and a tumor suppressor gene reveals anal cancer and precursor lesions. 

    Lorincz, AT; Nathan, M; Reuter, C; Warman, R; Thaha, MA; Sheaff, M; Vasiljevic, N; Ahmad, A; Cuzick, J; Sasieni, P (Impact Journals, 2017-08-01)
    We studied DNA methylation patterns of human papillomavirus (HPV) and tumor suppressor gene EPB41L3 in 148 anal and perianal biopsies to determine whether high levels of methylation would be associated with anal intraepithelial ...
  • Acceptability and Usability of iPrevent®, a Web-Based Tool for Assessment and Management of Breast Cancer Risk. 

    Lo, L; Collins, I; Bressel, M; Butow, P; Emery, J; Keogh, L; Weideman, P; Steel, E; Hopper, JL; Trainer, AH;... (American Association for Cancer Research, 2018-02)
    Background: iPrevent estimates an individual's personal BC risk, using either the IBIS or BOADICEA algorithms, and provides tailored risk management information on screening, lifestyle modifications, risk-reducing surgery ...
  • Meta-analysis of early nonmotor features and risk factors for Parkinson disease. 

    Noyce, AJ; Bestwick, JP; Silveira-Moriyama, L; Hawkes, CH; Giovannoni, G; Lees, AJ; Schrag, A (Wiley Online, 2012-07-10)
    OBJECTIVE: To evaluate the association between diagnosis of Parkinson disease (PD) and risk factors or early symptoms amenable to population-based screening. METHODS: A systematic review and meta-analysis of risk factors ...
  • Multiple Sclerosis - a review. 

    Dobson, R; Giovannoni, G (2018-10-09)
    Multiple sclerosis (MS) is the commonest non-traumatic disabling disease to affect young adults. The incidence of MS is increasing worldwide, together with the socioeconomic impact of disease. The underlying cause of MS, ...
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