Browsing Wolfson Institute of Preventive Medicine by Issue Date
Now showing items 1-20 of 2631
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BRCA awareness and testing experience in the UK Jewish population: a qualitative study
(BMJ Publishing Group, 04-04-2024)Background 1 in 40 UK Jewish individuals carry a pathogenic variant in BRCA1/BRCA2. Traditional testing criteria miss half of carriers, and so population genetic testing is being piloted for Jewish people in England. There ... -
Evaluation of system based Psychological First Aid training on the mental health proficiency of emergency medical first responders to natural disasters in China: a cluster randomised controlled trial
(BMJ Publishing Group, 06-05-2024)Objective To evaluate the effectiveness of a system based psychological first aid (PFA) training programme for emergency medical first responders in China. Design Parallel-group, assessor-blinded, cluster randomised ... -
Ovarian cancer: identifying and managing familial and genetic risk—summary of new NICE guidance
(BMJ Publishing Group, 09-05-2024) -
Changes in healthcare costs following genome-wide sequencing for children with developmental disorders and early onset seizures in England and Canada
(American Medical Association, 10-07-2024)Importance Etiologic diagnoses for rare diseases can involve a diagnostic odyssey, with repeated health care interactions and inconclusive diagnostics. Prior studies reported cost savings associated with genome-wide ... -
Identification of prodromal Parkinson's Disease - we may be able to but should we?
(Lippincott, Williams & Wilkins, 17-05-2024)Parkinson disease (PD) remains a progressive and incurable disease. Research over the past decade provides strong evidence of a detectible phase before the clinical diagnosis, known as the prodromal phase of PD (pPD). ... -
Exploring the benefits, harms, and costs of genomic newborn screening for rare diseases
(Nature Research, 19-06-2024) -
Efficient designs for three-sequence stepped wedge trials with continuous recruitment
(SAGE Publications, 21-05-2024)Background/Aims: The standard approach to designing stepped wedge trials that recruit participants in a continuous stream is to divide time into periods of equal length. But the choice of design in such cases is infinitely ... -
Human 3D ovarian cancer models reveal 1 malignant cell intrinsic and extrinsic factors that 2 influence CAR T cell activity
(31-05-2024)In vitro preclinical testing of chimeric antigen receptor (CAR) T cells is mostly carried out in monolayer cell cultures. However, alternative strategies are needed to take into account the complexity and the effects of ... -
EXPRESSED EMOTION AND AUDITORY EVOKED-POTENTIALS
(1990-05) -
The dose-response relationship between cigarette consumption, biochemical markers and risk of lung cancer.
(1997)The relationship between the number of cigarettes smoked per day and the incidence of lung cancer is linear but, from the multistage model of carcinogenesis, it should be quadratic (upwards curving). We investigated this ...