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Genetic testing for gynaecological cancer
(2017-01-01)
© 2016 Elsevier Ltd The traditional family-history approach to genetic testing involves taking a detailed three generation family-history from both sides of the family, ethnicity, type of cancer, age of onset and death. ...
Screening for gynecological cancers
(2013-03-11)
An estimated 17% of all new cancers in women worldwide are due to cancers of the cervix, the ovary and the uterus. Together, these cancers account for 14.6% of all female cancer deaths. This is a significant societal and ...
Systematic review of acceptability, cardiovascular, neurological, bone health and HRT outcomes following risk reducing surgery in BRCA carriers
(Elsevier, 2020-02-04)
© 2020 Primary surgical prevention in the form of risk-reducing salpingo-oophorectomy (RRSO) is the most effective option and the gold standard for ovarian cancer (OC) risk-reduction, particularly given the absence of an ...
Population Study of Ovarian Cancer Risk Prediction for Targeted Screening and Prevention
(MDPI AG, 2020-05-15)
Unselected population-based personalised ovarian cancer (OC) risk assessment combining genetic/epidemiology/hormonal data has not previously been undertaken. We aimed to perform a feasibility study of OC risk stratification ...
IMPACT OF POPULATION GENETIC TESTING AND OVARIAN CANCER RISK STRATIFICATION ON THE EMOTIONAL WELL-BEING AND HEALTH OF UNSELECTED WOMEN IN A GENERAL POPULATION
(BMJ Publishing Group Ltd., 2019-11-01)