One year in review 2020: pathogenesis of primary Sjögren's syndrome.
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Published version
Embargoed until: 5555-01-01
Reason: Version Not Permitted
Embargoed until: 5555-01-01
Reason: Version Not Permitted
Volume
38 Suppl 126
Pagination
3 - 9
Journal
Clin Exp Rheumatol
Issue
ISSN
0392-856X
Metadata
Show full item recordAbstract
The pathogenesis of primary Sjögren's syndrome (pSS) remains poorly understood. However, important efforts have been made during the last few months. In this review, following the others of this series we will summarise the most recent literature on pSS pathogenesis focusing in particular on new insights into pSS animal models, genetics and epigenetics, innate and adaptive immune system abnormalities and tertiary lymphoid structures. Hopefully, novel insights into pSS pathogenesis will pave the way to new therapeutic approaches to the disease improving patients' management and prognosis.