Browsing Experimental Medicine & Rheumatology by Issue Date

Biomechanical signals and the C-type natriuretic peptide counteract catabolic activities induced by IL-1 beta in chondrocyte/agarose constructs

Ramachandran, M; Achan, P; Salter, DM; Bader, DL; Chowdhury, TT (2011)

A comparative study of matrix metalloproteinase and aggrecanase mediated release of latent cytokines at arthritic joints

Mullen, L; Adams, G; Foster, J; Vessillier, S; Koester, M; Hauser, H; Layward, L; Gould, D; Chernajovsky, Y (2014-09)

Guidelines and Pathways for Clinical Practice in Tendinopathy: Their Role and Development

Morrissey, D (2015-11)

In-depth characterization of CD24(high)CD38(high) transitional human B cells reveals different regulatory profiles

Simon, Q; Pers, J-O; Cornec, D; Le Pottier, L; Mageed, RA; Hillion, S (2016-05)

SYNOVIAL MAST CELLS CORRELATE WITH LOCAL AND SYSTEMIC INFLAMMATION AND ARE FUNCTIONALLY ASSOCIATED WITH ECTOPIC LYMPHOID STRUCTURES IN PATIENTS WITH EARLY RHEUMATOID ARTHRITIS

Rivellese, F; Humby, F; Kelly, S; Nerviani, A; Mauro, D; Rocher-Ros, V; El Shikh, ME; de Paulis, A; Marone, G; Pitzalis, C (2016-06)

The Urokinase/Urokinase Receptor System in Mast Cells: Effects of its Functional Interaction with fMLF Receptors.

Rossi, FW; Prevete, N; Rivellese, F; Napolitano, F; Montuori, N; Postiglione, L; Selleri, C; de Paulis, A (2016-11)

Mast cell and basophils express the high affinity receptor for IgE (FcɛRI) and are primary effector cells of allergic disorders. The urokinase (uPA)-mediated plasminogen activation system is involved in physiological and ...

Mast cells in rheumatoid arthritis: friends or foes?

Rivellese, F; Nerviani, A; Rossi, FW; Marone, G; Matucci-Cerinic, M; de Paulis, A; Pitzalis, C (2017-06)

Resolution of inflammation by interleukin-9-producing type 2 innate lymphoid cells

Rauber, S; Luber, M; Weber, S; Maul, L; Soare, A; Wohlfahrt, T; Lin, N-Y; Dietel, K; Bozec, A; Herrmann, M (2017-08)

Synovial tissue research: a state-of-the-art review

Orr, C; Sousa, E; Boyle, DL; Buch, MH; Buckley, CD; Canete, JD; Catrina, AI; Choy, EHS; Emery, P; Fearon, U (2017-08)

The Relationship Between Synovial Pathobiology and Magnetic Resonance Imaging Abnormalities in Rheumatoid Arthritis: A Systematic Review

Humby, F; Mahto, A; Ahmed, M; Barr, A; Kelly, S; Buch, M; Pitzalis, C; Conaghan, PG (2017-09-01)

Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity

Taher, ET; Bystrom, J; Ong, VH; Isenberg, DA; Renaudineau, Y; Abraham, DJ; Mageed, RA (2017-10)

The long pentraxin PTX3: A prototypical sensor of tissue injury and a regulator of homeostasis

Erreni, M; Manfredi, AA; Garlanda, C; Mantovani, A; Rovere-Querini, P (2017-11)

Endothelial Dysfunction in Systemic Lupus Erythematosus: Pathogenesis, Assessment and Therapeutic Opportunities.

Mauro, D; Nerviani, A (2018)

BACKGROUND: Systemic Lupus Erythematosus (SLE) is characterised by increased mortality secondary to Cardiovascular Diseases (CVD). Despite being common in SLE, traditional cardiovascular risk factors cannot entirely justify ...

Mandatory vaccination in Italy: Time for engagement of immunologists

Mantovani, A; Santoni, A (2018-01)

Tuning inflammation and immunity by the negative regulators IL-1R2 and IL-1R8

Molgora, M; Supino, D; Mantovani, A; Garlanda, C (2018-01)

The RA-MAP Consortium: a working model for academia-industry collaboration.

Cope, AP; Barnes, MR; Belson, A; Binks, M; Brockbank, S; Bonachela-Capdevila, F; Carini, C; Fisher, BA; Goodyear, CS; Emery, P (2018-01)

Collaboration can be challenging; nevertheless, the emerging successes of large, multi-partner, multi-national cooperatives and research networks in the biomedical sector have sustained the appetite of academics and industry ...

TNFα in the regulation of Treg and Th17 cells in rheumatoid arthritis and other autoimmune inflammatory diseases.

Bystrom, J; Clanchy, FI; Taher, TE; Mangat, P; Jawad, AS; Williams, RO; Mageed, RA (2018-01)

TNFα is a principal pro-inflammatory cytokine vital for immunity to infections. However, its excessive production is involved in chronic inflammation and disease pathology in autoimmune diseases. Evidence for its pathogenic ...

Novel therapeutic approaches in Rheumatoid Arthritis: Role of Janus Kinases Inhibitors.

Rivellese, F; Lobasso, A; Barbieri, L; Liccardo, B; De Paulis, A; Rossi, FW (2018-02-09)

Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by synovial inflammation and hyperplasia, autoantibody production, cartilage and bone destruction and several systemic features. Cardiovascular, ...

ACKR2 in hematopoietic precursors as a checkpoint of neutrophil release and anti-metastatic activity

Massara, M; Bonavita, O; Savino, B; Caronni, N; Poeta, VM; Sironi, M; Setten, E; Recordati, C; Crisafulli, L; Ficara, F (2018-02-14)

Association of Defective Regulation of Autoreactive Interleukin-6-Producing Transitional B Lymphocytes With Disease in Patients With Systemic Sclerosis.

Taher, TE; Ong, VH; Bystrom, J; Hillion, S; Simon, Q; Denton, CP; Pers, J-O; Abraham, DJ; Mageed, RA (2018-03)

OBJECTIVE: Systemic sclerosis (SSc) has the highest case-specific mortality of any rheumatic disease, and no effective therapy is available. A clear manifestation of SSc is the presence of autoantibodies. However, the ...