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"This is the peer reviewed version of the following article: Scott, S.M., Simrén, M., Farmer, A.D., Dinning, P.G., Carrington, E.V., Benninga, M.A., Burgell, R.E., Dimidi, E., Fikree, A., Ford, A.C., Fox, M., Hoad, C.L., Knowles, C.H., Krogh, K., Nugent, K., Remes‐Troche, J.M., Whelan, K. and Corsetti, M. (2020), Chronic constipation in adults: Contemporary perspectives and clinical challenges. 1: Epidemiology, diagnosis, clinical associations, pathophysiology and investigation. Neurogastroenterology & Motility e14050. https://doi.org/10.1111/nmo.14050 which has been published in final form at https://doi.org/10.1111/nmo.14050. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions."