International Union of Basic and Clinical Pharmacology. XXX: Classification of receptors for 5-hydroxytryptamine; pharmacology and function
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Accepted version
Embargoed until: 2222-01-01
Reason: Version not permitted by publisher
Embargoed until: 2222-01-01
Reason: Version not permitted by publisher
Publisher
Journal
Pharmacological Reviews
ISSN
0031-6997
Metadata
Show full item recordAbstract
5-HT receptors expressed throughout the human body are targets for established therapeutics and various drugs in development. Their diversity of structure and function reflects the important role 5-HT receptors play in physiological and pathophysiological processes. The present review offers a framework for the official receptor nomenclature and a detailed understanding of each of the fourteen 5-HT receptor subtypes, their roles in the systems of the body and where appropriate the (potential) utility of therapeutics targeting these receptors.