Browsing Queen Mary University of London Theses by Issue Date
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Rotary Jet Spinning of Polymer Fibres
(Queen Mary University of London, 01/02/2019)Polymeric nanofibres can be produced from a variety of methods such as electrospinning and melt blowing, with fibres being produced having applications in many sectors such as biomedicine, composites and filtration. Existing ... -
Social and Cultural Risk and Protective Factors for Mental Health in East London Adolescents
(Queen Mary University of London, 01/03/2010)Background There is substantial evidence of the protective influence of social support on psychological distress in adults. Yet, levels of social support and psychological distress vary by ethnicity. There is little research ... -
Role of HOXA7 in growth and differentiation of human keratinocytes
(Queen Mary University of London, 01/03/2018)HOXA7 belongs to a family of homeobox transcription factors that are master regulators of cell differentiation, morphogenesis during embryonic development and cell proliferation. Dysregulation and non-nuclear localization ... -
Carbon Hybrids Electrocatalysts for Oxygen Reduction Reaction in Fuel Cells
(Queen Mary University of London, 01/03/2019)The oxygen reduction reaction (ORR) is a key reaction in fuel cells and metal-air batteries. This process involves multi-electron transfer and is kinetically sluggish due to the high-energy barriers required to break the ... -
Experimental Study of Oxidation, Ignition and Combustion of Aluminum Based Nanomaterials
(Queen Mary University of London, 01/05/2014)Aluminum based reactive nanomaterials have extensive applications in many fields including solid propellants, pyrotechnics, and catalytic reactions. One recent example is the novel concept of using nanostructured energetic ... -
Reverse Monte Carlo Studies of Inorganic Functional Materials Based on Neutron Scattering
(Queen Mary University of London, 01/05/2019)In this thesis, the crystal structure and atomic dynamics of four inorganic functional materials were studied based on powder neutron total scattering data. The studies focused on the structural features that depend on the ... -
The Genetics of Familial Leukaemia and Myelodysplasia
(Queen Mary University of London, 01/05/2019)Background & Aim: While the majority of myelodysplasia and acute myeloid leukaemia (MDS/AML) cases are sporadic, rare familial predisposition syndromes have been delineated and are regarded a separate disease entity in the ... -
Rethinking migrants’ financial lives: the role of risk in the everyday financial practices of migrants
(Queen Mary University of London, 01/07/2014)The overall aim of this thesis is to provide an holistic assessment of the financial practices of migrants in advanced Western economies using the analytical lens of risk. More specifically, this research argues that a ... -
Investigating Clustering in Trisomy 18 and Trisomy 13
(Queen Mary University of London, 01/07/2014)Trisomies 18 and 13 are rare genetic conditions (occurring around 1 in 6,000 and 10,000 newborns respectively) which are caused by an extra copy of either chromosome 18 or 13, similar to trisomy 21 (Down syndrome). The ... -
The Role of miRNAs from the 14q32 Region in Acquired Resistance to Lapatinib
(Queen Mary University of London, 01/07/2019)HER2 is over-expressed in 20-25 % of breast cancers. Due to the increase in proliferation and survival signalling resulting from HER2 over-expression, this sub-type is associated with more aggressive tumour progression and ... -
Pentoxifylline in anaemia resistant to erythropoietin (PEAR) study A double blind placebo controlled randomised trial
(Queen Mary University of London, 01/08/2019)Background Hyporesponsiveness to erythropoiesis-stimulating agents (ESA) and its association with adverse cardiovascular outcomes remains a considerable problem in patients with end-stage renal disease (ESRD) undergoing ... -
Studies on the Programmable Protein Assembly via Genetically Encoded Native Chemical Ligation
(Queen Mary University of London, 01/10/2019)Programmed protein assembly has vast potential in applications as diverse as bioreactors, smart materials and drug delivery. However, to realise this potential, exact control of the assembly process is required. Thus, this ... -
ECOLOGICAL SHIFTS OF STREAM ECOSYSTEMS IN A DEGLACIATING AREA OF THE EUROPEAN ALPS
(Queen Mary University of London, 01/10/2019)This thesis provides a contribution to the knowledge on the effects of deglaciation on alpine stream ecosystems, taking into account also the hydroecological influence of thawing permafrost and paraglacial features. With ... -
Studies on the self-assembly of geometrically designed protein fusions using genetically programmed chemistry
(Queen Mary University of London, 02/01/2019)Self-assembling proteins have great potential to be applied to a myriad of biotechnological applications. The engineering of these proteins to create modules that will assemble into user-defined structures is a key challenge ... -
iRHOM2 in skin disease and oesophageal cancer
(Queen Mary University of London, 02/02/2015)Mutations in RHBDF2, the gene encoding inactive rhomboid protein iRHOM2, result in the dominantly inherited condition Tylosis with oesophageal cancer (TOC). TOC causes plamoplantar keratoderma, oral precursor lesions and ... -
CHARACTERISING FACTORS PREDICTIVE OF INFECTION IN SEVERELY INJURED PATIENTS
(Queen Mary University of London, 02/02/2015)Infection after trauma complicates the patients clinical course. Infection leads to longer critical care and hospital stays, has been associated with increased mortality rates and places considerable cost pressures on ... -
Random Structures
(Queen Mary University of London, 02/02/2015)For many combinatorial objects we can associate a natural probability distribution on the members of the class, and we can then call the resulting class a class of random structures. Random structures form good models of ... -
RECTAL HYPOSENSITIVITY: CLINICAL AND PHYSIOLOGICAL IMPACT ON PATIENTS WITH CHRONIC CONSTIPATION
(Queen Mary University of London, 02/04/2014)Intact rectal sensation is integral to normal anorectal function. Rectal hyposensitivity (RH) implies diminished rectal sensory perception and is currently diagnosed using standard anorectal physiology tests. There is ... -
Automatic Music Transcription using Structure and Sparsity
(Queen Mary University of London, 02/05/2014)Automatic Music Transcription seeks a machine understanding of a musical signal in terms of pitch-time activations. One popular approach to this problem is the use of spectrogram decompositions, whereby a signal matrix is ... -
Microcapsule internalization by cells in vitro caused by physical and biochemical stimuli
(Queen Mary University of London, 02/05/2014)There is a growing interest in micro sized vehicles with the function of storing, targeting and controlled releasing of substances during the past few decades. However, delivering the desired drugs inside micro containers ...