Browsing Centre for Tumour Biology by Title
Now showing items 77-96 of 374
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DIAP2 functions as a mechanism-based regulator of drICE that contributes to the caspase activity threshold in living cells.
(2007-12-31)In addition to their well-known function in apoptosis, caspases are also important in several nonapoptotic processes. How caspase activity is restrained and shut down under such nonapoptotic conditions remains unknown. ... -
Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in Covid-19.
(2021-07-09)Rationale: Resolution mechanisms are central in both the maintenance of homeostasis and the return to catabasis following tissue injury and/or infections. Amongst the pro-resolving mediators, the essential fatty acid-derived ... -
Drice restrains Diap2-mediated inflammatory signalling and intestinal inflammation
(Springer Nature, 2021-07-14) -
Endothelial Jagged1 promotes solid tumor growth through both pro-angiogenic and angiocrine functions
(Impact Journals, LLC, 2015-06-08)Angiogenesis is an essential process required for tumor growth and progression. The Notch signaling pathway has been identified as a key regulator of the neo-angiogenic process. Jagged-1 (Jag1) is a Notch ligand required ... -
Evolution of Premalignant Disease
(2017-12)