Browsing Centre for Tumour Biology by Title
Now showing items 312-331 of 378
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SNPnexus COVID: Facilitating the Analysis of COVID-19 Host Genetics
(Fortune Journals, 2021) -
A somatic genetic clock for clonal species.
(Nature Research, 2024-06-10)Age and longevity are key parameters for demography and life-history evolution of organisms. In clonal species, a widespread life history among animals, plants, macroalgae and fungi, the sexually produced offspring (genet) ... -
Spatially constrained tumour growth affects the patterns of clonal selection and neutral drift in cancer genomic data
(2019)Quantification of the effect of spatial tumour sampling on the patterns of mutations detected in next-generation sequencing data is largely lacking. Here we use a spatial stochastic cellular automaton model of tumour growth ... -
The Spectrin cytoskeleton regulates the Hippo signalling pathway.
(2015-04-01)The Spectrin cytoskeleton is known to be polarised in epithelial cells, yet its role remains poorly understood. Here, we show that the Spectrin cytoskeleton controls Hippo signalling. In the developing Drosophila wing and ... -
STARPAC clinical trial
(Elsevier, 2020-12) -
Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth.
(Springer Verlag, 2013-01-23)BACKGROUND: Regulation of lipid metabolism via activation of sterol regulatory element binding proteins (SREBPs) has emerged as an important function of the Akt/mTORC1 signaling axis. Although the contribution of dysregulated ...