Browsing Centre for Translational Medicine & Therapeutics by Title
Now showing items 833-844 of 844
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Vagal determinants of exercise capacity
(2017-05-18) -
Vasospastic myocardial infarction caused by a slimming agent-do not forget non-prescription drugs.
(2017-04)A 41-year-old woman presented with central chest discomfort. She had been previously well, was an ex-smoker and reported no regular medication. The ECG developed T-wave changes inferiorly and anterolaterally and troponin ... -
Volume of surgery during the COVID-19 pandemic in England and Wales: comparative analysis using routinely collected population level data
(Queen Mary University of London: Critical Care and Perioperative Medicine Research Group, 2021)The healthcare response to the COVID-19 pandemic has required rapid changes to the provision of secondary care services, requiring re-deployment of staff and equipment from other departments. Surgical services represent a ... -
The whole truth and nothing but the truth: the need for full reporting of randomised trials.
(2015)The use of cardiac output monitoring to guide fluid and inotropic therapy in surgical patients has remained a controversial topic for more than 40 years. The reasons for this are numerous and complex, but key amongst them ... -
Withholding or withdrawing of life-sustaining therapy in older adults (>= 80 years) admitted to the intensive care unit
(Springer Berlin Heidelberg, 2018-05-17)PURPOSE: To document and analyse the decision to withhold or withdraw life-sustaining treatment (LST) in a population of very old patients admitted to the ICU. METHODS: This prospective study included intensive care ... -
X-Linked Immunodeficient Mice With No Functional Bruton's Tyrosine Kinase Are Protected From Sepsis-Induced Multiple Organ Failure
(Frontiers Media, 2020-10-07)We previously reported the Bruton's tyrosine kinase (BTK) inhibitors ibrutinib and acalabrutinib improve outcomes in a mouse model of polymicrobial sepsis. Now we show that genetic deficiency of the BTK gene alone in Xid ...