Browsing Centre for Translational Medicine & Therapeutics by Title

1623: EFFECT OF ANGIOTENSIN II ON VASOPRESSOR DOSE AND SAFETY IN PATIENTS WITH SEVERE VASODILATORY SHOCK

Ferrada, P; Strumwasser, A; Zarbock, A; Mackey, C; Wilkinson, J; Handisides, D; Prowle, J (2019-01-01)

2-Hydroxyglutarate Metabolism Is Altered in an in vivo Model of LPS Induced Endotoxemia.

Fitzpatrick, SF; Lambden, S; Macias, D; Puthucheary, Z; Pietsch, S; Mendil, L; McPhail, MJW; Johnson, RS (Frontiers Media, 2020-03-03)

The metabolic response to endotoxemia closely mimics those seen in sepsis. Here, we show that the urinary excretion of the metabolite 2-hydroxyglutarate (2HG) is dramatically suppressed following lipopolysaccharide (LPS) ...

531 Less Is More: Extensive Cardiac Investigations Add Little Value in Waitlisting Patients for Kidney Transplantation

Chow, BJ; Khurram, MA; Capuano, E; Pugliese, F; Yaqoob, MM; Mohamed, IH (2022)

AB0042 Identification of Sulfido-Conjugated Mediators That Promote Resolution of Infection and Organ Protection

Dalli, J; Chiang, N; Serhan, C (2016-06-01)

Abstinence from alcohol consumption and exercise capacity: A pre and post intervention cohort study

Raj, AS; Cobain, C; Abbott, TEF; Cron, N

Abstract 14913: Renal Function Underpins Cox-2: Methylarginine Axis in Mouse and Man

Ferreira, PM; Kirkby, N; Vaja, R; Pires, ML; Crescente, M; Liu, B; Yu, H; Chan, M; Nuesing, R; Zhou, Y (Wolters Kluwer, 2022-11-08)

Abstracts

Unknown author (2015-06)

ACE and response to pulmonary rehabilitation in COPD: two observational studies.

Kon, SSC; Jolley, CJ; Shrikrishna, D; Montgomery, HE; Skipworth, JRA; Puthucheary, Z; Moxham, J; Polkey, MI; Man, WD-C; Hopkinson, NS (2017)

INTRODUCTION: Skeletal muscle impairment is an important feature of chronic obstructive pulmonary disease (COPD). Renin-angiotensin system activity influences muscle phenotype, so we wished to investigate whether it affects ...

Acquired bloodstream infection in the intensive care unit: incidence and attributable mortality

Prowle, JR; Echeverri, JE; Ligabo, EV; Sherry, N; Taori, GC; Crozier, TM; Hart, GK; Korman, TM; Mayall, BC; Johnson, PDR (2011)

Acquired loss of cardiac vagal activity is associated with myocardial injury in patients undergoing noncardiac surgery: prospective observational mechanistic cohort study.

May, SM; Reyes, A; Martir, G; Reynolds, J; Paredes, LG; Karmali, S; Stephens, RCM; Brealey, D; Ackland, GL (2019-12)

BACKGROUND: Myocardial injury is more frequent after noncardiac surgery in patients with preoperative cardiac vagal dysfunction, as quantified by delayed heart rate (HR) recovery after cessation of cardiopulmonary exercise ...

Active GSK3β and an intact β-catenin TCF complex are essential for the differentiation of human myogenic progenitor cells

LEWIS, F; Agley, C; Jaka, O; Lazarus, N; Velloso, C; Francis-West, P; Ellison-Hughes, G; Harridge, S (Nature, 2017-10-13)

Acute flail tricuspid valve from blunt trauma

Fazzini, B; Coulter, C; Puthucheary, Z; Shepherd, S (2023)

Acute hyperglycaemic crisis after vaccination against COVID-19: A case series.

Edwards, AE; Vathenen, R; Henson, SM; Finer, S; Gunganah, K (2021-06-29)

Vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are the most important component of the global response to the COVID-19 pandemic. Although most adverse reactions observed have been mild, the ...

Acute kidney injury and adverse outcomes of critical illness: correlation or causation?

Girling, BJ; Channon, SW; Haines, RW; Prowle, JR (2020-04)

Acute Kidney Injury and Risk of Death After Elective Surgery: Prospective Analysis of Data From an International Cohort Study

Chaudery, H; MacDonald, N; Ahmad, T; Chandra, S; Tantri, A; Sivasakthi, V; Mansor, M; Matos, R; Pearse, RM; Prowle, JR (2019-05)

Acute Kidney Injury in COVID-19: multicentre prospective analysis of registry data

Wan, YI; Bien, Z; Apea, VJ; Orkin, CM; Dhairyawan, R; Kirwan, CJ; Pearse, RM; Puthucheary, ZA; Prowle, JR (2021-03-27)

Acute Kidney Injury in COVID-19: secondary analysis of prospective data from the EthICAL study

Prowle, J; Wan, Y; Bien, Z (Queen Mary University of London: Critical Care and Perioperative Medicine Research Group, 2021)

Statistical Analysis Plan – This secondary analysis of the EthICAL study will focus on the incidence, risk factors and outcomes associated with AKI within COVID-19 patients admitted to five acute hospitals in East London. ...

Acute kidney injury in the critically ill: an updated review on pathophysiology and management.

Pickkers, P; Darmon, M; Hoste, E; Joannidis, M; Legrand, M; Ostermann, M; Prowle, JR; Schneider, A; Schetz, M (2021-07-02)

Acute kidney injury (AKI) is now recognized as a heterogeneous syndrome that not only affects acute morbidity and mortality, but also a patient's long-term prognosis. In this narrative review, an update on various aspects ...

Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model

Haines, RW; Lin, S-P; Hewson, R; Kirwan, CJ; Torrance, HD; O'Dwyer, MJ; West, A; Brohi, K; Pearse, RM; Zolfaghari, P (2018-02-26)

Acute Skeletal Muscle Wasting in Critical Illness

Puthucheary, ZA; Rawal, J; McPhail, M; Connolly, B; Ratnayake, G; Chan, P; Hopkinson, NS; Padhke, R; Dew, T; Sidhu, PS (American Medical Association, 2013-10-16)

Importance Survivors of critical illness demonstrate skeletal muscle wasting with associated functional impairment. Objective To perform a comprehensive prospective characterization of skeletal muscle wasting, defining ...