Browsing Centre for Microvascular Research (CMR) by Title
Now showing items 97-105 of 105
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TCL1 transgenic mice as a model for CD49d-high chronic lymphocytic leukemia
(Springer Nature, 2020-02-21) -
TIGIT expressing CD4+T cells represent a tumor-supportive T cell subset in chronic lymphocytic leukemia
(Taylor & Francis, 2017-09-21)While research on T cell exhaustion in context of cancer particularly focuses on CD8C cytotoxic T cells, the role of inhibitory receptors on CD4C T-helper cells have remained largely unexplored. TIGIT is a recently identified ... -
Tuning the endothelial response: differential release of exocytic cargos from Weibel-Palade Bodies.
(Wiley, 2018-06-28)BACKGROUND: Endothelial cells harbour specialised storage organelles, Weibel-Palade Bodies (WPBs). Exocytosis of WPB content into the vascular lumen initiates primary haemostasis, mediated by Von Willebrands factor (VWF) ... -
Tuning the endothelial response: differential release of exocytic cargos from Weibel-Palade bodies.
(2018-09)Essentials Endothelial activation initiates multiple processes, including hemostasis and inflammation. The molecules that contribute to these processes are co-stored in secretory granules. How can the cells control release ...