Browsing Centre for Microvascular Research (CMR) by Issue Date
Now showing items 1-20 of 113
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A naturally occurring calcineurin variant inhibits FoxO activity and enhances skeletal muscle regeneration
(Rockefeller University Press, 2007-12-17) -
The junctional adhesion molecule JAM-C regulates polarized transendothelial migration of neutrophils in vivo
(2011-08)The migration of neutrophils into inflamed tissues is a fundamental component of innate immunity. A decisive step in this process is the polarized migration of blood neutrophils through endothelial cells (ECs) lining the ... -
A feeder-free, human plasma-derived hydrogel for maintenance of a human embryonic stem cell phenotype in vitro.
(BioMed Central Ltd., 2012-08-08)BACKGROUND: Human embryonic stem cells (hESCs) represent a tremendous resource for cell therapies and the study of human development; however to maintain their undifferentiated state in vitro they routinely require the use ... -
A novel role for syndecan-3 in angiogenesis.
(2013)Syndecan-3 is one of the four members of the syndecan family of heparan sulphate proteoglycans and has been shown to interact with numerous growth factors via its heparan sulphate chains. The extracellular core proteins ... -
Evaluation of a novel non-destructive catch and release technology for harvesting autologous adult stem cells.
(Public Library of Science, 2013-01-22)BACKGROUND: Cell based therapies are required now to meet the critical care needs of paediatrics and healthy ageing in an increasingly long-lived human population. Repair of compromised tissue by supporting autologous ... -
Carbonic anhydrase activation is associated with worsened pathological remodeling in human ischemic diabetic cardiomyopathy.
(2014-03-26)BACKGROUND: Diabetes mellitus (DM) has multifactorial detrimental effects on myocardial tissue. Recently, carbonic anhydrases (CAs) have been shown to play a major role in diabetic microangiopathy but their role in the ... -
Shed syndecan-2 inhibits angiogenesis
(2014-11-01) -
The role of CD44 in the pathophysiology of chronic lymphocytic leukemia
(Frontiers Media, 2015-04-20)CD44 interactions with hyaluronan (HA) play a key role in various malignancies, supporting tumor cell migration, adhesion, and survival. In contrast to solid tumors, the expression of CD44 standard and variant forms and ... -
Leukotriene B4-Neutrophil Elastase Axis Drives Neutrophil Reverse Transendothelial Cell Migration In Vivo.
(2015-06-01)Breaching endothelial cells (ECs) is a decisive step in the migration of leukocytes from the vascular lumen to the extravascular tissue, but fundamental aspects of this response remain largely unknown. We have previously ...