This is the peer reviewed version of the following article: Ma, B., Whiteford, J. R., Nourshargh, S. and Woodfin, A. (2016), Underlying chronic inflammation alters the profile and mechanisms of acute neutrophil recruitment. J. Pathol.. Accepted Author Manuscript. doi:10.1002/path.4776, which has been published in final form at https://dx.doi.org/10.1002/path.4776. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Self-Archiving.