Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Title
Now showing items 383-402 of 471
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SCREENING SIRNA EFFICACY USING HIGH THROUGHPUT FLUORESCENCE SYSTEM IN VITRO.
(Elsevier, 2022-04) -
Selective autoantibody production by Yaa+ B cells in autoimmune Yaa(+)-Yaa- bone marrow chimeric mice.
(Rockefeller University Press, 1991-11-01)The accelerated autoimmune syndrome observed in BXSB/MpJ male mice is associated with the presence on the Y chromosome of an as yet unidentified mutant gene, designated Y chromosome-linked autoimmune acceleration (Yaa). ... -
Serum and tissue biomarkers associated with CRESS and STAR response to B-cell targeted therapy in TRACTISS trial of Sjogren's syndrome
(Oxford University Press, 2023-12-10)OBJECTIVES: To identify peripheral and salivary gland (SG) biomarkers of response/resistance to B-cell depletion based on the novel concise CRESS (cCRESS) and candidate STAR composite endpoints. METHODS: Longitudinal ... -
Severe Aortic Valve Regurgitation in Relapsing Polychondritis.
(Lippincott, Williams & Wilkins, 2018-03) -
Shared and Distinct Aspects of the Sepsis Transcriptomic Response to Fecal Peritonitis and Pneumonia.
(2017-08-01)RATIONALE: Heterogeneity in the septic response has hindered efforts to understand pathophysiology and develop targeted therapies. Source of infection, with different causative organisms and temporal changes, might influence ... -
Single cell analysis of RA synovial B cells reveals a dynamic spectrum of ectopic lymphoid B cell activation and hypermutation characterized by NR4A nuclear receptor expression
(2021-05-16)<h4>ABSTRACT</h4> Ectopic lymphoid structures (ELS) can develop in rheumatoid arthritis (RA) synovial tissue, but the precise pathways of B cell activation and selection are not well understood. Here, we identified a unique ... -
SLEEP DISTURBANCES IN LUPUS PATIENTS
(2019-04) -
Spectrum: fast density-aware spectral clustering for single and multi-omic data
(Oxford University Press, 2019-09-10)Motivation Clustering patient omic data is integral to developing precision medicine because it allows the identification of disease subtypes. A current major challenge is the integration multi-omic data to identify a ...