Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Title
Now showing items 237-256 of 464
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Lymphomas complicating primary Sjögren's syndrome: from autoimmunity to lymphoma.
(Oxford University Press (OUP), 2019-03-05)Lymphoma development is the most serious complication of SS and the main factor impacting on mortality rate in patients with this condition. Lymphomas in SS are most commonly extranodal non-Hodgkin B-cell lymphomas of the ... -
M3C: Monte Carlo reference-based consensus clustering
(bioRxiv, 2019-12-04)Abstract: Genome-wide data is used to stratify patients into classes for precision medicine using clustering algorithms. A common problem in this area is selection of the number of clusters (K). The Monti consensus clustering ... -
M3C: Monte Carlo reference-based consensus clustering.
(2020-02-04)Genome-wide data is used to stratify patients into classes for precision medicine using clustering algorithms. A common problem in this area is selection of the number of clusters (K). The Monti consensus clustering algorithm ... -
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution.
(2023-12)The human leukocyte antigen (HLA) locus plays a critical role in complex traits spanning autoimmune and infectious diseases, transplantation and cancer. While coding variation in HLA genes has been extensively documented, ... -
Markedly different pathogenicity of four immunoglobulin G isotype-switch variants of an antierythrocyte autoantibody is based on their capacity to interact in vivo with the low-affinity Fcgamma receptor III.
(2000-04-17)Using three different Fcgamma receptor (FcgammaR)-deficient mouse strains, we examined the induction of autoimmune hemolytic anemia by each of the four immunoglobulin (Ig)G isotype-switch variants of a 4C8 IgM antierythrocyte ... -
Mast Cells in Early Rheumatoid Arthritis
(2019-04-02)