Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Title
Now showing items 192-211 of 470
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IL-36, IL-37, and IL-38 Cytokines in Skin and Joint Inflammation: A Comprehensive Review of Their Therapeutic Potential.
(2019-03-13)The interleukin (IL)-1 family of cytokines is composed of 11 members, including the most recently discovered IL-36α, β, γ, IL-37, and IL-38. Similar to IL-1, IL-36 cytokines are initiators and amplifiers of inflammation, ... -
Immune checkpoint inhibitor PD-1 pathway is down-regulated in synovium at various stages of rheumatoid arthritis disease progression.
(Public Library of Science, 2018-02-28)Immune checkpoint blockade with therapeutic anti-cytotoxic T lymphocyte-associated antigen (CTLA)-4 (Ipilimumab) and anti-programmed death (PD)-1 (Nivolumab and Pembrolizumab) antibodies alone or in combination has shown ... -
Immunosuppressive therapy with rituximab in common variable immunodeficiency.
(BMC (part of Springer Nature), 2019-05-06)Common variable immunodeficiency (CVID) is the most frequent symptomatic primary antibody deficiency in adulthood and is characterized by the marked reduction of IgG and IgA serum levels. Thanks to the successful use of ... -
Impaired IL‐27 Mediated Control of CD4+ T Cell Function Impacts on Ectopic Lymphoid Structure Formation in Patients with Sjögren's Syndrome
(Wiley, 2020-04-20)This is the pre-peer reviewed version of the following article: Lucchesi, D., Coleby, R., Pontarini, E., Prediletto, E., Rivellese, F., Hill, D.G., Derrac Soria, A., Jones, S.A., Humphreys, I.R., Sutcliffe, N., Tappuni, ... -
Implementing treat-to-target urate-lowering therapy during hospitalisations for gout flares.
(Oxford University Press, 2023-10-31)OBJECTIVES: To evaluate a strategy designed to optimise care and increase uptake of urate-lowering therapy (ULT) during hospitalisations for gout flares. METHODS: We conducted a prospective cohort study to evaluate a ... -
Impulse response analysis of an ultrasonic human body channel
(Elsevier, 2020-04-01) -
In a surgical model of OA female mice compared to males display pain at an early stage of disease and differential regulation of pain sensitizers
(2021-04)Meeting Abstract from British Society for Matrix Biology Autumn 2020 Meeting.