Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Title
Now showing items 80-99 of 471
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Community Assessment of the Predictability of Cancer Protein and Phosphoprotein Levels from Genomics and Transcriptomics.
(2020-08-26)Cancer is driven by genomic alterations, but the processes causing this disease are largely performed by proteins. However, proteins are harder and more expensive to measure than genes and transcripts. To catalyze developments ... -
Comparative analysis of late-stage rheumatoid arthritis and osteoarthritis reveals shared histopathological features.
(2023-11-19)OBJECTIVES: Osteoarthritis (OA) is a debilitating and heterogeneous condition, characterized by various levels of articular cartilage degradation, osteophytes formation, and synovial inflammation. Multiple evidences suggest ... -
Comparison of ESSDAI and ClinESSDAI in potential optimisation of trial outcomes in primary Sjogren's syndrome: examination of data from the UK Primary Sjogren's Syndrome Registry
(EMH Swiss Medical Publishers Ltd., 2018-02-07)OBJECTIVES: To assess the use of the Clinical EULAR Sjogren's Syndrome Disease Activity Index (ClinESSDAI), a version of the ESSDAI without the biological domain, for assessing potential eligibility and outcomes for clinical ... -
Complement activation selectively potentiates the pathogenicity of the IgG2b and IgG3 Isotypes of a high affinity anti-erythrocyte autoantibody
(Rockefeller University Press, 2002-03-18) -
Connective Tissue Degeneration: Mechanisms of Palmar Fascia Degeneration (Dupuytren's Disease).
(Springer, 2016-07-14)Dupuytren's disease is a connective tissue disorder of the hand causing excessive palmar fascial fibrosis with associated finger contracture and disability. The aetiology of the disease is heterogeneous, with both genetic ... -
Corrigendum to “Activation of Melanocortin Receptors MC1 and MC5 Attenuates Retinal Damage in Experimental Diabetic Retinopathy”
(Hindawi Publishing Corporation, 2021-04-02) -
Corrigendum: Eligibility for clinical trials in primary Sjögren's syndrome: Lessons from the UK Primary Sjögren's Syndrome Registry [Rheumatology, 55, (2016) (544-552)] doi:10.1093/rheumatology/kev373
(2017-08-18)This is a correction to: Rheumatology, Volume 55, Issue 3, March 2016, Pages 544–552, https://doi.org/10.1093/rheumatology/kev373 -
Corrigendum: The RA-MAP Consortium: a working model for academia-industry collaboration.
(2018-01-24)This corrects the article DOI: 10.1038/nrrheum.2017.200. -
Culture expansion in low-glucose conditions preserves chondrocyte differentiation and enhances their subsequent capacity to form cartilage tissue in three-dimensional culture.
(2014-02-01)Culture conditions that preserve a stable chondrocyte phenotype are desirable in cell-based cartilage repair to maximize efficacy and clinical outcome. This study investigates whether low-glucose conditions will preserve ... -
Current practice, guideline adherence, and barriers to implementation for Achilles tendinopathy rehabilitation: a survey of physical therapists and people with Achilles tendinopathy.
(2024)OBJECTIVE: To explore clinical practice patterns of physical therapists (PTs) who treat people with Achilles tendinopathy (AT), and identify perceived barriers and facilitators for prescribing and engaging with therapeutic ... -
Current views on the pathogenesis of Sjögren's syndrome.
(Wolters Kluwer Health, Inc., 2018-03)PURPOSE OF REVIEW: The purpose of this review is to provide an insight into the pathophysiological mechanisms involved in the pathogenesis of primary Sjögren's Syndrome (pSS), highlighting recent findings with potential ... -
Deconstruction of rheumatoid arthritis synovium defines inflammatory subtypes.
(2023-11)Rheumatoid arthritis is a prototypical autoimmune disease that causes joint inflammation and destruction1. There is currently no cure for rheumatoid arthritis, and the effectiveness of treatments varies across patients, ...