Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Title
Now showing items 204-223 of 471
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Impaired IL‐27 Mediated Control of CD4+ T Cell Function Impacts on Ectopic Lymphoid Structure Formation in Patients with Sjögren's Syndrome
(Wiley, 2020-04-20)This is the pre-peer reviewed version of the following article: Lucchesi, D., Coleby, R., Pontarini, E., Prediletto, E., Rivellese, F., Hill, D.G., Derrac Soria, A., Jones, S.A., Humphreys, I.R., Sutcliffe, N., Tappuni, ... -
Implementing treat-to-target urate-lowering therapy during hospitalisations for gout flares.
(Oxford University Press, 2023-10-31)OBJECTIVES: To evaluate a strategy designed to optimise care and increase uptake of urate-lowering therapy (ULT) during hospitalisations for gout flares. METHODS: We conducted a prospective cohort study to evaluate a ... -
Impulse response analysis of an ultrasonic human body channel
(Elsevier, 2020-04-01) -
In a surgical model of OA female mice compared to males display pain at an early stage of disease and differential regulation of pain sensitizers
(2021-04)Meeting Abstract from British Society for Matrix Biology Autumn 2020 Meeting. -
Increased frequency of circulating IL-21 producing Th-cells in patients with granulomatosis with polyangiitis (GPA).
(2013)INTRODUCTION: The present study aimed to explore a possible role for IL-21 producing Th-cells in the immunopathogenesis of granulomatosis with polyangiitis (GPA). METHODS: Peripheral blood from 42 GPA patients in remission ... -
Increased hip adduction during running is associated with patellofemoral pain and differs between males and females: A case-control study.
(2019-06-25)Patellofemoral pain is common amongst recreational runners and associated with altered running kinematics. However, it is currently unclear how sex may influence kinematic differences previously reported in runners with ... -
Increased plasma levels of Gas6 and its soluble tyrosine kinase receptors Mer and Axl are associated with immunological activity and severity of lupus nephritis.
(2020-06-04)OBJECTIVES: Growth arrest-specific 6 (Gas6) and its receptors have been shown to play a crucial role in the homeostasis of the innate immune system by regulating apoptosis and inflammation. We aimed to verify whether an ... -
Influence of plasma processing on recovery and analysis of circulating nucleic acids.
(2013)Circulating nucleic acids (CNAs) are under investigation as a liquid biopsy in cancer. However there is wide variation in blood processing and methods for isolation of circulating free DNA (cfDNA) and microRNAs (miRNAs). ... -
Influence of the age at diagnosis in the disease expression of primary Sjögren syndrome. Analysis of 12,753 patients from the Sjögren Big Data Consortium.
(2021)OBJECTIVES: To analyse how the main components of the disease phenotype (sicca symptoms, diagnostic tests, immunological markers and systemic disease) can be driven by the age at diagnosis of primary Sjögren's syndrome ... -
Integrating physical activity promotion into UK medical school curricula: testing the feasibility of an educational tool developed by the Faculty of Sports and Exercise Medicine.
(2020)Background: At present education on exercise medicine and physical activity (PA) promotion does not feature heavily within the medical curriculum. Objectives: The purpose of this study was to test the feasibility of a ...