Browsing Centre for Experimental Medicine and Rheumatology (EMR) by Title
Now showing items 103-122 of 471
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Derived myeloid lineage induced pluripotent stem as a platform to study human C-C chemokine receptor type 5Δ32 homozygotes.
(Elsevier, 2023-10-26)The C-C chemokine receptor type 5 (CCR5) expressed on immune cells supports inflammatory responses by directing cells to the inflammation site. CCR5 is also a major coreceptor for macrophage tropic human immunodeficiency ... -
Detection of HER2 amplification in circulating free DNA in patients with breast cancer.
(2011-04-12)BACKGROUND: Human epidermal growth factor receptor 2 (HER2) is amplified and overexpressed in 20-25% of breast cancers. This study investigated circulating free DNA (cfDNA) for detection of HER2 gene amplification in ... -
Developing a diagnostic framework for patients presenting with Exercise Induced Leg Pain (EILP): a scoping review.
(2023-11-21)BACKGROUND: Numerous conditions are grouped under the generic term exercise-induced leg pain (EILP), yet clear diagnostic guidelines are lacking. This scoping review was conducted to clarify the definition and diagnostic ... -
Developing Clinical and Research Priorities for Pain and Psychological Features in People With Patellofemoral Pain: An International Consensus Process With Health Care Professionals.
(2022-01)OBJECTIVE: To decide clinical and research priorities on pain features and psychological factors in persons with patellofemoral pain. DESIGN: Consensus development process. METHODS: We undertook a 3-stage process consisting ... -
Digital Interventions to Support Adolescents and Young Adults With Cancer: Systematic Review.
(2019-07-31)BACKGROUND: The last decade has seen an increase in the number of digital health interventions designed to support adolescents and young adults (AYAs) with cancer. OBJECTIVE: The objective of this review was to identify, ... -
Distinct transcriptional responses of mouse sensory neurons in models of human chronic pain conditions.
(2018)Background: Sensory neurons play an essential role in almost all pain conditions, and have recently been classified into distinct subsets on the basis of their transcriptomes. Here we have analysed alterations in dorsal ... -
Does Pain at an Earlier Stage of Chondropathy Protect Female Mice Against Structural Progression After Surgically Induced Osteoarthritis?
(2020-06-30)OBJECTIVE: Female C57BL/6 mice exhibit less severe chondropathy than male mice. This study was undertaken to test the robustness of this observation and explore underlying mechanisms. METHODS: Osteoarthritis was induced ...