dc.contributor.author | Parsons, N | |
dc.contributor.author | Griffin, XL | |
dc.contributor.author | Achten, J | |
dc.contributor.author | Chesser, TJ | |
dc.contributor.author | Lamb, SE | |
dc.contributor.author | Costa, ML | |
dc.date.accessioned | 2021-05-24T16:46:10Z | |
dc.date.available | 2021-05-24T16:46:10Z | |
dc.date.issued | 2018-01-01 | |
dc.identifier.citation | Parsons, N., Griffin, X. L., Achten, J., Chesser, T., Lamb, S. E., & Costa, M. (2018). Modelling and estimation of health-related quality of life after hip fracture: A re-analysis of data from a prospective cohort study. Bone and Joint Research, 7(1), 1–5. | en_US |
dc.identifier.issn | 2046-3758 | |
dc.identifier.uri | https://qmro.qmul.ac.uk/xmlui/handle/123456789/72035 | |
dc.description.abstract | OBJECTIVES: This study investigates the reporting of health-related quality of life (HRQoL) in patients following hip fracture. We compare the relative merits and make recommendations for the use for two methods of measuring HRQoL; (i) including patients who died during follow-up and (ii) including survivors only. METHODS: The World Hip Trauma Evaluation has previously reported changes in HRQoL using EuroQol-5D for patients with hip fractures. We performed additional analysis to investigate the effect of including or excluding those patients who died during the first four months of the follow-up period. RESULTS: The dataset included 503 patients, 25 of whom died between 30 days and four months of injury. There was a statistically significant difference in 30-day HRQoL between those alive (mean 0.331 and standard deviation (sd) 0.360) and those dead (mean 0.156 and sd 0.421) by four months (independent-samples t-test; p 0.022). The estimated difference of 0.175 in HRQoL (95% confidence interval 0.025 to 0.325) was also highly clinically significant. CONCLUSION: When reporting HRQoL for patients after a hip fracture, excluding patients who die during follow-up leads to an overestimate of the effects of the intervention or treatment pathway. We would recommend that death-adjusted estimates should be used routinely when reporting HRQoL in this population.Cite this article: N. Parsons, X. L. Griffin, J. Achten, T. J. Chesser, S. E. Lamb, M. L. Costa. Modelling and estimation of health-related quality of life after hip fracture: A re-analysis of data from a prospective cohort study. Bone Joint Res 2018;7:1-5. | en_US |
dc.format.extent | 1 - 5 | |
dc.language | eng | |
dc.publisher | British Editorial Society of Bone and Joint Surgery | en_US |
dc.relation.ispartof | Bone Joint Res | |
dc.rights | This is an open-access article distributed under the terms of the Creative Commons Attributions licence (CC-BY-NC), which permits unrestricted use, distribution, and reproduction in any medium, but not for commercial gain, provided the original author and source are credited. | |
dc.subject | EQ-5D | en_US |
dc.subject | Health-related quality of life | en_US |
dc.subject | Hip fracture | en_US |
dc.subject | Longitudinal models | en_US |
dc.title | Modelling and estimation of health-related quality of life after hip fracture: A re-analysis of data from a prospective cohort study. | en_US |
dc.type | Article | en_US |
dc.rights.holder | © 2018 Parsons et al. | |
dc.identifier.doi | 10.1302/2046-3758.71.BJR-2017-0199 | |
pubs.author-url | https://www.ncbi.nlm.nih.gov/pubmed/29292297 | en_US |
pubs.issue | 1 | en_US |
pubs.notes | Not known | en_US |
pubs.publication-status | Published | en_US |
pubs.publisher-url | https://doi.org/10.1302/2046-3758.71.BJR-2017-0199 | |
pubs.volume | 7 | en_US |
dcterms.dateAccepted | 2017-09-06 | |
rioxxterms.funder | Default funder | en_US |
rioxxterms.identifier.project | Default project | en_US |